Covid-19 variants keep emerging in different parts of the world, causing experts to ask how long the pandemic will last, and how effective the current methods of protection really are.

Since the pandemic started in 2019, people have referred to the disease which has paralyzed the world simply as ‘coronavirus’. Now, in 2021, when we talk about it, we mean not just the original variant, but also its numerous mutations. 

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In May, the WHO decided to label the key variants with Greek letters. Since then, the Delta variant has been proclaimed the predominant strain across the world, and now we have titles that look like codes to detail the differences between variants. Last month, the UK was put on high alert over a fast-spreading Delta AY.4.2 variant. This week, Norway reported finding one more version of the Delta strain – AY. 63. The country’s experts suggest it’s not more dangerous than the Delta mutation itself. Meanwhile, another Covid variant, discovered in France (B.1.640), brought the researchers an unpleasant surprise: they said they’d never seen mutations like it. 

Professor David Dockrell, from the Center for Inflammation Research of the University of Edinburgh, described to RT the reasons for the constant mutation of the coronavirus. “The areas in the virus that are most likely to change are those that come into contact with what we call ‘selective pressures’ – or factors that make them need to change,” he explains. “So, a version of the virus which mutates and changes to give it a selective advantage to escape from the immune system is more likely to prosper and become a dominant strain.” 

That’s how it works: The part of the virus many of the immune responses (or antibodies, T-cells etc.) are responding to is called the spike protein (or the S-protein). So, the virus tries to change it in order to survive. 

“We know that a variety of different viruses are able to mutate and change when exposed to the selective pressure of the immune system, whether it would be the human immune system or other species in which these viruses have evolved,” Prof. Dockrell says. “And of course, we’ve seen it most clearly with HIV, which is particularly good at changing and evolving. It does something called ‘reverse transcription’ – it copies material in the reversed direction from DNA to RNA.” 

Covid is still seemingly running faster than humanity’s efforts to curb it, but Prof. Dockrell has some good news. “The coronavirus – and viruses like it – are not as able to make these changes. They are going to do it to some extent, but they are not going to be as successful as retroviruses and HIV.” 

And the other major thing to say: When the viruses make changes, there’s always what we call ‘a fitness cost’. Many of the potential changes that the virus could make will actually not favor its survival. So there are only a certain number, potentially, of changes that the virus can make, before it starts affecting its fitness. 

Now, unfortunately, we are still in a phase where Covid19 can continue to evolve and change. It’s not time to panic, though, because across the world various ways to adapt the current anti-Covid strategies are already in place. First of all, people should keep getting vaccines – maybe receiving slightly altered booster doses, Prof. Dockrell suggests, “in a way, that we, after all, have to do with influenza, by providing a seasonal influenza vaccine and changing it every year.” 

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“And maybe we have to keep changing some of the treatments like these new monoclonal antibodies against the virus, because they also may be limited by the emergence of a mutation of the virus evolving the S-protein,” he adds. 

Sounds promising – but won’t it become a never-ending race against constantly emerging mutations? 

Hopefully not. According to Prof. Dockrell, there are parts of viruses that scientists call ‘conserved areas’. With time, vaccines and monoclonal antibodies will target these areas, which the virus finds very hard to change. “Clearly, the direction of travel is to develop either vaccine responses that affect more different kinds of virus, or these ‘monoclonal antibodies’ that we could use to prevent or treat infection, that they will target more conserved areas and therefore will be less limited by the ability of these virus to evolve and change,” he concludes.

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Any apology for Nazism is unacceptable, Colombia’s president Ivan Duque has insisted, after photos of police academy cadets dressed up in Third Reich uniforms were uploaded online, causing outrage.

“Any apology for Nazism is unacceptable,” Duque stated in a tweet on Friday. The president said he condemned any references to those who were “responsible for the Jewish Holocaust that claimed the lives of more than 6 million people,” adding that “anti-Semitism has no place in the world.”

Duque had earlier made demands for “heads to roll” at an academy that “promotes such criminal practices,” with its director, Lieutenant Colonel Jorge Ferney Bayona Sanchez, already having been sacked.

Colombia’s defense ministry, which oversees the country’s police, also insisted in a statement that that its training programs “don’t envisage in any way an activity such as the one which took place” at the academy.

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The images of police cadets in Nazi uniforms caused anger and bewilderment among internet users.

The German and Israeli embassies in the country reacted by issuing a joint statement, in which they expressed “total rejection of any form of apology or demonstration of Nazism.” The US embassy in Bogota also said that it was “shocked and deeply disappointed” by the development.

The controversial images, in which aspiring officers were caught sporting black SS outfits with red swastika armbands and grey Wehrmacht uniforms from the World War II era, weren’t revealed in some bombshell media report, but were actually published on the official Twitter account of the Colombian police this Thursday.

The photos were taken as part of a “cultural exchange” event at the police academy in the city of Tulua, aimed at commemorating Germany and “strengthening the knowledge of our police students.” The cosplay was apparently intended to illustrate the history of German law enforcement, with more cadets pictured wearing more modern versions of the country’s police uniforms in the pictures.

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Scientists have used artificial intelligence to “predict” formulas for new designer drugs, with the stated goal of helping to improve their regulation. The AI generated formulas for nearly nine million potential new drugs.

Researchers with the University of British Columbia (UBC) used a deep neural net for the job, teaching it to make up chemical structures of potential new drugs. According to their study, released this week, the computer intelligence fared better at the task than the scientists had expected.

The research team used a database of known designer drugs – synthetic psychoactive substances – to train the AI on their structures. The market for designer drugs is ever-changing, since their manufacturers are constantly tweaking their formulas to circumvent restrictions and produce new “legal” substances, while cracking their structure takes months for law enforcement agencies, the researchers said.

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“The vast majority of these designer drugs have never been tested in humans and are completely unregulated. They are a major public-health concern to emergency departments across the world,” one of the researchers, UBC medical student Dr. Michael Skinnider has said.

After its training, the AI was able to generate some 8.9 million potential designer drugs. Afterwards, researchers ran a data sheet of some 196 new drugs, which had emerged in real life after the model was trained, and found that more than 90% of these have been already predicted by the computer.

“The fact that we can predict what designer drugs are likely to emerge on the market before they actually appear is a bit like the 2002 sci-fi movie, Minority Report, where foreknowledge about criminal activities about to take place helped significantly reduce crime in a future world,” senior author Dr. David Wishart, a professor of computing science at the University of Alberta, has said.

Identifying completely unknown substances remains an issue for the AI, the research team has noted, but they hope it might potentially help with that task, since the computer was also able to predict which formulas of designer drugs were more likely to be created and hit the market. The model “ranked the correct chemical structure of an unidentified designer drug among the top 10 candidates 72 percent of the time,” while throwing in spectrometry analysis, which is an easily obtained measurement, bumped the accuracy to some 86%.

“It was shocking to us that the model performed this well, because elucidating entire chemical structures from just an accurate mass measurement is generally thought to be an unsolvable problem,” Skinnider stated.

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Rotterdam Mayor Ahmed Aboutaleb has described an anti-lockdown protest in his city as an “orgy of violence.” The Dutch demonstration devolved into a violent riot that saw police open fire on protesters.

Aboutaleb described the events of Friday night as an “orgy of violence,” after protesters packed Rotterdam’s central Coolsingel shopping street to voice their opposition to an ongoing partial lockdown, a ban on New Year’s Eve fireworks displays, and the possibility of a two-tiered system of freedom in the Netherlands, one of liberty for the vaccinated and restrictions for those without the jab.

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A police squad car is seen engulfed in flames during a protest in Rotterdam, Netherlands, November 19, 2021.
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The protest soon got out of hand, and police said on Saturday that 57 people were arrested. Protesters were seen torching police vehicles and launching fireworks at police, who shot at them in response.

Aboutaleb said that the cops had been “forced” to use their weapons. “On a number of occasions the police felt it necessary to draw their weapons to defend themselves,” he told reporters. “They shot at protesters, people were injured.”

Police say at least seven people were injured. Two of these injuries were caused by police bullets, and the victims are still in hospital. One officer was hospitalized, while several others were treated at the scene for minor injuries.

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Sporadic clashes broke out at massive Saturday demonstrations in major European cities, as thousands of people took to the streets of Vienna, Paris and Rome to express their discontent with Covid-19 restrictions.

The Austrian capital Vienna on Saturday saw the largest protest turnout since the start of the Covid-19 pandemic. A total of 38,000 people took to the city streets to join a dozen demonstrations protesting government measures.

The protests came a day after the Austrian authorities ordered nationwide compulsory vaccination from February 1 and imposed a full lockdown, starting Monday. The massive procession that spanned over several kilometers marched along Vienna’s central ring road. The city center was paralyzed for several hours as traffic was restricted.

Austria’s right-wing Freedom Party, whose members joined the rallies, put the number of protesters at 100,000. Some demonstrations were also attended by members of various far-right groups. The protests were generally peaceful but footage published by Ruptly video news agency showed several scuffles between the police and the demonstrators breaking out.

Law enforcement spoke of a total of five arrests. One incident saw a protester attempting to grab an officer’s gun and take it from its holster. In another incident, the officers were pelted with bottles and fireworks and had to use pepper spray in response.

Hundreds of kilometers away from Vienna, in the French capital Paris, events took a more dramatic turn. There, a demonstration against the government Covid-19 measures coincided with the third anniversary of the Yellow Vests movement. Hundreds of protesters took part in the protest, which quickly turned into clashes between the demonstrators and law enforcement.

The protesters were building barricades and setting them on fire as well as pelting police with bottles and various other projectiles. Law enforcement responded with profuse amounts of tear gas, sometimes filling entire streets with thick smoke to disperse the crowds.

Rome saw a massive demonstration against Italy’s Covid-19 health pass, also known as the Green Pass. Some 4,000 people gathered in the center of the Italian capital, according to the police. The demonstrators were waving national flags and chanting “Freedom” and “No Green Pass,” referring to the vaccination certificate needed to enter various public venues such as clubs or bars.

The crowd staged a sit-in in the Circus Maximus – an ancient Roman chariot-racing stadium converted into a modern-day park. They remained there after sunset, lighting the area with thousands of phones and colored smoke bombs. The rally was peaceful, though, as the police did not report any incidents.

Unlike Rome, Italy’s northern city of Milano saw clashes between protesters and the police as law enforcement officers sought to break up an unauthorized rally at the city center. Large police forces were deployed to the city center and several squares were cordoned off.

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Protesters thronged the streets of Australian cities on Saturday, demanding an end to what they called the “tyranny” and “oppression” of lockdowns, vaccine mandates, and the proposed expansion of the government’s pandemic powers.

In Melbourne, Sky News reporter Sophie Elsworth described “tens of thousands of people streaming through the streets.” The march came after a week of smaller protests aimed at Victoria Premier Dan Andrews’ controversial pandemic bill, which if approved by the state’s legislature would allow Andrews and Health Minister Martin Foley to declare an indefinite state of emergency and issue public health orders by decree – including “any order… that the minister believes is reasonably necessary to protect public health.”

Should the bill pass, it would allow Andrews to target certain classes of people with these orders, categorizing them by age, occupation, or vaccination status. Fines for noncompliance would range from up to AU$21,800 for people and AU$109,000 for businesses.

Alternative media sources claimed that more than 100,000 people showed up to protest. However, the demonstration remained free of the violent clashes seen at protests in Melbourne in recent months.

“Australia has been willing to send troops to all parts of the world to help people become free,” one military veteran told a crowd of listeners during the protest. “To now be fighting oppression here in our own country, it’s saddening.”

Huge numbers of protesters also turned out in Sydney, and although more than 600 police officers were deployed to watch over the gathering, no arrests were made, 9News reported.

Holding signs decrying state “tyranny,” the demonstrators chanted “freedom” and called for the firing of state politicians who have implemented a two-tier system where the unvaccinated are denied many of the privileges extended to the fully jabbed.

Similarly massive gatherings took place in Adelaide, Brisbane, and Perth, with no notable incidents of violence or police action. Further afield, protests are taking place in more than 120 cities around the world this weekend, in a loosely coordinated event dubbed the ‘Worldwide Rally For Freedom’ by activists.

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Protests against renewed Covid-19 restrictions turned violent in The Hague. The unrest comes a day after several demonstrators in another Dutch city, Rotterdam, were injured amid police gunfire.

Seven people were arrested after fierce clashes broke out between law enforcement and anti-lockdown demonstrators in The Hague, the seat of the International Court of Justice (ICJ), on Saturday.

A video shared on social media shows protesters lighting firecrackers that sparked multiple fires, causing the skies in the city to glow an eerie red.

In another clip, a group of protesters could be seen knocking down a traffic pole fitted with a surveillance camera.

Dutch police reported that five of its officers were injured in the showdown with rioters. One officer was taken to hospital with a knee injury and concussion. Two others “suffered hearing damage,” while another two suffered injuries to their hands.

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A burned electric scooter is seen after an anti-lockdown protest in Rotterdam, Netherlands, November 19, 2021 © AFP / Jeffrey Groeneweg
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The chaotic scenes in the Netherlands’ third-largest city unfolded a day after a protest against reimposed Covid-19 restrictions in Rotterdam was marred by violence. Over 50 people were arrested in the city and three were injured after police opened fire in a bid to quell the unrest. Police later claimed that officers were “compelled to shoot at targets” to protect themselves. The three injured protesters remain in hospital, and their condition is unknown.

Protests have swept through a number of Dutch cities after the Netherlands became the first country in Western Europe since summer to go into a partial lockdown last week. Tensions soared further after the government banned New Year’s Eve fireworks displays and the Dutch parliament backed the introduction of the so-called 2G system, which would bar the unvaccinated and those who have not recently recovered from the virus from a long list of public places if introduced.

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After vowing to retaliate against Lithuania’s move to allow Taiwan open a “representative office” in Vilnius, Beijing has announced it is downgrading diplomatic relations with the Baltic state.

In a statement on Sunday, the Chinese foreign ministry said that China’s diplomatic relations with Lithuania will be formally lowered to the level of charge d’affaires, while blasting Vilnius for setting a “bad international precedent” by giving the island the green light to open its mission in the Lithuanian capital.

The ministry went on to accuse Vilnius of undermining the One China principle and the principle of neutrality in bilateral relations, explaining its decision to demote relations by citing the need to “safeguard its sovereignty and the basic norms of international relations.”

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The Lithuanian flag (FILE PHOTO) © REUTERS/Ints Kalnins
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“The Lithuanian government must bear all the consequences arising from this,” the ministry said, while calling on Vilnius to “correct its mistakes immediately.”

“No matter how the ‘Taiwan independence’ forces distort facts and reverse black and white, they cannot change the historical fact that the mainland and Taiwan belong to the same China,” the ministry asserted.

The move comes just two days after Beijing went on a verbal offensive against the Baltic country, warning that pushback for its cozying up to Taiwan would be imminent. “As to what necessary measures China will take, you may wait and see,” it said at the time.

Lithuania and China have been embroiled in a diplomatic row and have not maintained relations at ambassadorial level since September. After the Baltic state revealed that it would be opening a de facto Taiwanese embassy, China withdrew its ambassador from the country in August. Vilnius followed suit the following month.

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A gunman injured two civilians, one of them fatally, and two police officers before being shot dead by security forces near Jerusalem’s Western Wall on Sunday morning, Israeli poice said.

The civilian victims were taken to Shaare Zedek Medical Center. One, who was in his 30s, succumbed to his injuries at the hospital. The other, a 46-year-old, is said to have suffered moderate injuries. Two police officers were hurt by shrapnel.

In a video clip shared on social media and purportedly filmed at the scene, multiple gunshots could be heard amid agitated shouting. Security officers could then be seen standing around what appears to be a dead body. Witnesses speculated it was that of a “terrorist.”

The gunman, whose identity was not immediately disclosed, was killed during the incident. Police said he had used a homemade submachine gun.

DETAILS TO FOLLOW

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When the PRC decides to move on Taiwan, it is unlikely to move in a manner that makes a US decision on intervention clear cut.  Should China decide, initially at least, against a full-scale invasion of that island nation, it could instead opt to try to “win without fighting.” Beijing might do so by using its large, state-controlled fishing fleet to cut smaller Taipei-controlled islands off from Taiwan itself much as the PRC is now massing fishing boats to expand Chinese-controlled seas to press claims on the Japanese Senkakus and Whitsun Reef in Philippine waters. Chinese state-owned fisheries companies – part of the so-called ‘Maritime Militia’ – serve as fronts for PLA intelligence. Using their fleets to operate in a manner somewhere between peace and conflict in the gray zone of contested control around Taiwan would allow Beijing to test whether the US and its allies are willing to help defend the island’s independence without being seen to initiate open conflict.

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