General Joseph L. Votel (Ret.) joined BENS as CEO & President in January 2020 following a 39-year military career where he commanded special operations and conventional forces at every level; last serving as the Commander of U.S. Central Command (CENTCOM) where he was responsible for U.S. and coalition military operations in the Middle East, Levant, and Central and South Asia. General Votel’s career included combat in Panama, Afghanistan, and Iraq and he led the 79-member coalition that successfully liberated Iraq and Syria from the Islamic State Caliphate. General Votel preceded his assignment at CENTCOM with service as the Commander of U.S. Special Operations Command and the Joint Special Operations Command.

The Cipher Brief:  Did you ever envision that the U.S. would pull out so quickly or completely leaving the Afghan military on its own without U.S. air support?  

General Votel: I did not anticipate this during my time – but once the President sets a hard departure date – then a fast withdrawal is inevitable.  No Commander wants to accept unnecessary risk with troops on the ground when you are up against a clearly articulated departure date.

The Cipher Brief: Intelligence assessments wildly missed the mark on how fast Kabul would fall, what factors contributed most directly to this? 

General Votel: Certainly, the departure of our own capabilities is a big part of this; the lack of direct contact with Afghan leaders is another important factor; and, of course, once it was clear that we were departing (and took our Commander out) — we lost priority and access with our normal and reliable Afghan intelligence sources.

The Cipher Brief: U.S. personnel are facing a deteriorating security situation at the Kabul airport while U.S. forces are still deploying for the contingency operation, another sign that the administration underestimated how fast the Taliban would reach Kabul. The U.S. could have chosen to slow the Taliban advance using airpower, why didn’t it happen, do you think? 


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General Votel: I think it is very clear that this was no longer a priority for our Government.  The mission right now, at least articulated over the weekend, is about supporting evacuation of the diplomats and helping with the departure of those Afghans who assisted the US and meet the criteria for evacuation.  While I don’t know this for certain — I believe what we were trying to do with over the horizon air support in a rapidly developing situation, was not optimal or overly effective.  It doesn’t seem to have done much – if anything.

The Cipher Brief: The U.S. has allowed U.S. supplied military hardware, weapons and technology to fall into the hands of the Taliban, a group responsible for the deaths of U.S. personnel and thousands of innocent Afghans.  The U.S. government holds private citizens and corporations accountable for far lesser violations of export violations involving dual-use technology or military equipment, etc.  How should Americans think about this situation now, where the Taliban will use equipment, paid for the by the U.S. taxpayer, to potentially perpetrate acts of violence against U.S. interests, and erode democratic values that the U.S. tried to introduce to Afghanistan?  

General Votel: Not sure on this.  Unfortunately, it is not the first time we have seen this — remember ISIS in 2014, in Mosul?  I suspect these will be more trophy pieces than they will be hard military capability – with the exception of small arms, mortars, and artillery.  Most of this will be difficult for the Taliban to sustain – and they probably prefer their own gear, anyway.

The Cipher Brief:  There is a lot of anger among the national security community right now.  What would you say to individuals who have suffered because of the U.S. role in Afghanistan, who may be feeling anger and rage?  

General Votel: I can’t really comment on anger in the national security community — I am sure that exists, but the sentiment that seems more strong to me, is disappointment.  No one wants what we are seeing now.  I think most security professionals can accept a decision to depart by the Commander in Chief — that is well within his authority, and everyone understands this; what is harder to accept is the manner in which this happened, and how it has played out.  It was hard for me to watch Taliban sitting at a conference table that I once sat at with the Afghan President.  In a number of public engagements, I have participated in lately – people have asked me if this whole effort was a waste.  My response has been consistent.  American military personnel, members of the IC and the diplomatic corps conducted themselves honorably throughout this war.  They responded when the Nation called and did their best for our Country, each other, and the Afghan people.  There will be plenty of time to place the blame – but the vast, vast majority of Americans who participated in some aspect of the Afghan War did so nobly and to the best of their ability.  We should not lose sight of this.  That this did not turn out the way we all hoped — is not their fault … and I would not want anyone (especially families of our wounded and killed) to think these efforts were in vain.  That is not how I thought about them at the time, and it is not how I think about them now.  They answered when the Nation called.

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Vaccination of all Hungarian citizens against Covid-19 is inevitable, PM Viktor Orban has said, stating that even the most hardline anti-vaxxers will ultimately face a choice between dying with the virus and getting a jab.

Speaking to Kossuth radio on Friday, the Hungarian leader lashed out at those reluctant to get vaccinated against coronavirus, branding them a threat “not only to themselves but to all others.”

In the end, everyone will have to be vaccinated; even the anti-vaxxers will realize that they will either get vaccinated or die. So, I urge everyone to take this opportunity.

The EU member state is currently experiencing its fourth wave of coronavirus, Orban stated, blaming the situation on those who had not got vaccinated. “If everybody were inoculated, there would be no fourth wave or it would be just a small one,” the PM claimed.

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Covid rates take Germany to ‘nationwide state of emergency’

Apart from urging the unvaccinated to go and finally get their jabs, Orban also promoted booster shots, revealing that he had already taken three doses of a coronavirus vaccine.

“The only thing that protects us from the virus is vaccination. And we are now also seeing, at least the experts are unanimous in saying, that four to six months after the second vaccination, the protective power of the vaccine weakens. Therefore, a third vaccination is justified,” he said.

Hungary has already announced new anti-Covid measures, though somewhat short of the strict measures proposed by the nation’s Medical Chamber on Wednesday. The medical body called for a blanket ban on mass events, and suggested making entry to restaurants, theaters and other indoor venues conditional on bearing a Covid-19 inoculation certificate. Instead, Budapest rolled out compulsory mask wearing for most indoor environments, as well as making booster shots mandatory for all medical workers, starting from Saturday.

A nation of 10 million, Hungary’s total tally of logged Covid cases is hovering just below the one million mark. On Friday, it registered a new daily record, with nearly 11,300 new Covid infections. More than 32,700 people in Hungary have succumbed to the disease over the course of the pandemic.

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The planned introduction of chemical castration for serial rapists in Pakistan has been dropped due to objections from experts in Islamic law, who said such punishment would be counter to Sharia.

The controversial clause in a bill amending criminal law in Pakistan was dropped before the National Assembly voted on it on Wednesday, a parliament official said on Friday. If it were passed, it would have been unconstitutional, Parliamentary Secretary for Law and Justice Maleeka Bokhari explained. The basic law of the country requires all its laws to be in line with the Sharia and the Koran.

Bokhari said the decision to drop the clause was taken due to objections from the Council of Islamic Ideology, a constitutional body that advises the government of Pakistan on the intricacies of Islamic law.

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The bill amends Pakistan’s Penal Code and Criminal Procedure Code to streamline investigations and prosecutions of sexual crimes as part of wider anti-rape reform. Some conservative lawmakers vocally argued against the castration clause as the piece of legislation was moving towards approval. Senator Mushtaq Ahmed from the Islamist Jamaat-i-Islami party argued that rapists should be hanged publicly, while castration was never mentioned in Sharia.

A separate bill also approved by the parliament on Wednesday introduces a system of special regional investigators for rape allegations to be appointed by the prime minister, as well as new protections for victims, and punishments for officials who fail to investigate their complaints properly. Among other things, it makes evidence that a victim is “generally of immoral character” inadmissible in court.

The reform is necessary because currently deterrence of sexual crimes in Pakistan is undermined by “poor investigation, archaic procedures and rules of evidence and delay in the trial,” the bill said.

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Talk about a gift that keeps on giving; each month reveals yet another beautiful pooch answering nature’s call. Also important: $1 from each “Pooping Pooches 2022” calendar is donated to the Maui Humane Society to support animals in need. This tasteful calendar is available on Etsy and Amazon, but you can also get 500 piece jigsaw puzzle for those long, dark winter evenings!

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

Pooping Pooches 2022 calendar.

This year’s latest addition is a 500 piece jigsaw puzzle which can also be purchased on Amazon (not suitable for babies and individuals who have a tendency to put things in their mouth and potentially choke on the pieces).

Pooping Pooches jigsaw puzzle.

Pooping Pooches jigsaw puzzle.

Just like the calendar, every puzzle sale will also contribute to Maui Humane Society to help animals in need (one poop at a time).

Pooping Pooches helps animals in need.

Anyways, if pooping dogs is something you would like to look at for a whole year, you can get this calendar on Etsy or Amazon.

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Objects, including spacecraft, could pierce through the universe using several black holes as a ‘shortcut’, a new study suggests.

The new theory posited by French physicist Pascal Koiran marks a break from earlier research in the field of black hole studies. Previously, it was thought that a so-called ‘wormhole’ composed of two black holes would be prone to instantly collapse, thus making it impossible for an object to successfully travel all the way from one side and out the other. However, by employing different metrics, the French scientist’s new model has arrived at a very different conclusion: “We show that the particle reaches the wormhole throat for a finite value t′1 of the time marker t′.” In essence, that means an object, for instance, a spacecraft, could pass through this wormhole portal intact and reach some far-away region of the universe, taking far less time than would be needed if traveling conventionally.

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The study in its entirety will see the light of day in the upcoming issue of the Journal of Modern Physics D, though an abstract has been available since early October.

Yet, there are too many ifs as to whether this purely theoretical model has any bearing on the way the universe actually works. For starters, to create such a time-and-space tunnel you would need a regular black hole and a so-called white hole, which is essentially a black hole in reverse. While black holes never let anything out, their ‘twins’ never let anything in. So, according to Albert Einstein’s theory of general relativity and Nathan Rosen’s additions to it, if you were to connect the two, they would make up a bridge across time and space. However, if the laws postulated by another branch of physics, thermodynamics, are anything to go by, such a construct would be highly unstable. Perhaps more importantly, the very existence of white holes has yet to be proven beyond a reasonable doubt. At present, they remain a pure theorization, thus putting any talk of space-and-time portals on rather shaky ground.

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A Roadmap for AI in the Intelligence Community

(Editor’s Note: This article was first published by our friends at Just Security and is the fourth in a series that is diving into the foundational barriers to the broad integration of AI in the IC – culture, budget, acquisition, risk, and oversight.  This article considers a new IC approach to risk management.)

OPINION — I have written previously that the Intelligence Community (IC) must rapidly advance its artificial intelligence (AI) capabilities to keep pace with our nation’s adversaries and continue to provide policymakers with accurate, timely, and exquisite insights. The good news is that there is strong bipartisan support for doing so. The not-so-good news is that the IC is not well-postured to move quickly and take the risks required to continue to outpace China and other strategic competitors over the next decade.

In addition to the practical budget and acquisition hurdles facing the IC, there is a strong cultural resistance to taking risks when not absolutely necessary. This is understandable given the life-and-death nature of intelligence work and the U.S. government’s imperative to wisely execute national security funds and activities. However, some risks related to innovative and cutting-edge technologies like AI are in fact necessary, and the risk of inaction – the costs of not pursuing AI capabilities – is greater than the risk of action.

The Need for a Risk Framework

For each incredible new invention, there are hundreds of brilliant ideas that have failed. To entrepreneurs and innovators, “failure” is not a bad word. Rather, failed ideas are often critical steps in the learning process that ultimately lead to a successful product; without those prior failed attempts, that final product might never be created. As former President of India A.P.J. Abdul Kalam once said, “FAIL” should really stand for “First Attempt In Learning.”

The U.S. government, however, is not Silicon Valley; it does not consider failure a useful part of any process, especially when it comes to national security activities and taxpayer dollars. Indeed, no one in the U.S. government wants to incur additional costs or delay or lose taxpayer dollars. But there is rarely a distinction made within the government between big failures, which may have a lasting, devastating, and even life-threatening impact, and small failures, which may be mere stumbling blocks with acceptable levels of impact that result in helpful course corrections.


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As a subcommittee report of the House Permanent Select Committee on Intelligence (HPSCI) notes “[p]rogram failures are often met with harsh penalties and very public rebukes from Congress which often fails to appreciate that not all failures are the same. Especially with cutting-edge research in technologies … early failures are a near certainty …. In fact, failing fast and adapting quickly is a critical part of innovation.” There is a vital difference between an innovative project that fails and a failure to innovate. The former teaches us something we did not know before, while the latter is a national security risk.

Faced with congressional hearings, inspector general reports, performance evaluation downgrades, negative reputational effects, and even personal liability, IC officers are understandably risk-averse and prefer not to introduce any new risk. That is, of course, neither realistic nor the standard the IC meets today. The IC is constantly managing a multitude of operational risks – that its officers, sources, or methods will be exposed, that it will miss (or misinterpret) indications of an attack, or that it will otherwise fail to produce the intelligence policymakers need at the right time and place. Yet in the face of such serious risks, the IC proactively and aggressively pursues its mission. It recognizes that it must find effective ways to understand, mitigate, and make decisions around risk, and therefore it takes action to make sure potential ramifications are clear, appropriate, and accepted before any failure occurs. In short, the IC has long known that its operations cannot be paralyzed by a zero-risk tolerance that is neither desirable nor attainable. This recognition must also be applied to the ways in which the IC acquires, develops, and uses new technology.

This is particularly important in the context of AI. While AI has made amazing progress in recent years, the underlying technology, the algorithms and their application, are still evolving and the resulting capabilities, by design, will continue to learn and adapt. AI holds enormous promise to transform a variety of IC missions and tasks, but how and when these changes may occur is difficult to forecast and AI’s constant innovation will introduce uncertainty and mistakes. There will be unexpected breakthroughs, as well as failures in areas that initially seemed promising.

The IC must rethink its willingness to take risks in a field where change and failure is embraced as part of the key to future success. The IC must experiment and iterate its progress over time and shift from a culture that punishes even reasonable risk to one that embraces, mitigates, and owns it. This can only be done with a systematic, repeatable, and consistent approach to making risk-conscious decisions.

Today there is no cross-IC mechanism for thinking about risk, let alone for taking it. When considering new activities or approaches, each IC element manages risk through its own lens and mechanisms, if at all. Several individual IC elements have created internal risk assessment frameworks to help officers understand the risks of both action and inaction, and to navigate the decisions they are empowered to make depending upon the circumstances. These frameworks increase confidence that if an activity goes wrong, supervisors all the way up the chain will provide backing as long as the risk was reasonable, well-considered and understood, and the right leaders approved it. And while risk assessments are often not precise instruments of measurement – they reflect the quality of the data, the varied expertise of those conducting the assessments, and the subjective interpretation of the results – regularized and systematic risk assessments are nevertheless a key part of effective risk management and facilitate decision-making at all levels.


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Creating these individual frameworks is commendable and leading-edge for government agencies, but more must be done holistically across the IC. Irregular and inconsistent risk assessments among IC elements will not provide the comfort and certainty needed to drive an IC-wide cultural shift to taking risk. At the same time, the unique nature of the IC, comprised of 18 different elements, each with similar and overlapping, but not identical, missions, roles, authorities, threats and vulnerabilities, does not lend itself to a one-size-fits-all approach.

For this reason, the IC needs a flexible but common strategic framework for considering risk that can apply across the community, with each element having the ability to tailor that framework to its own mission space. Such an approach is not unlike how the community is managed in many areas today – with overarching IC-wide policy that is locally interpreted and implemented to fit the specific needs of each IC element. When it comes to risk, creating an umbrella IC-wide framework will significantly improve the workforce’s ability to understand acceptable risks and tradeoffs, produce comprehensible and comparable risk determinations across the IC, and provide policymakers the ability to anticipate and mitigate failure and unintended escalation.

Critical Elements of a Risk Framework

A common IC AI risk framework should inform and help prioritize decisions from acquisition or development, to deployment, to performance in a consistent way across the IC. To start, the IC should create common AI risk management principles, like its existing principles of transparency and AI ethics, that include clear and consistent definitions, thresholds, and standards. These principles should drive a repeatable risk assessment process that each IC element can tailor to its individual needs, and should promote policy, governance, and technological approaches that are aligned to risk management.

The successful implementation of this risk framework requires a multi-disciplinary approach involving leaders from across the organization, experts from all relevant functional areas, and managers who can ensure vigilance in implementation. A whole-of-activity methodology that includes technologists, collectors, analysts, innovators, security officers, acquisition officers, lawyers and more, is critical to ensuring a full 360-degree understanding of the opportunities, issues, risks, and potential consequences associated with a particular action, and to enabling the best-informed decision.

Given the many players involved, each IC element must strengthen internal processes to manage the potential disconnects that can lead to unintended risks and to create a culture that instills in every officer a responsibility to proactively consider risk at each stage of the activity. Internal governance should include an interdisciplinary Risk Management Council (RMC) made up of senior leaders from across the organization. The RMC should establish clear and consistent thresholds for when a risk assessment is required, recommended, or not needed given that resource constraints likely will not allow all of the broad and diverse AI activities within organizations to be assessed. These thresholds should be consistent with the IC risk management principles so that as IC elements work together on projects across the community, officers have similar understandings and expectations.

The risk framework itself should provide a common taxonomy and process to:

  • Understand and identify potential failures, including the source, timeline, and range of effects.
  • Analyze failures and risks by identifying internal vulnerabilities or predisposing conditions that could increase the likelihood of adverse impact.
  • Evaluate the likelihood of failure, taking into consideration risks and vulnerabilities.
  • Assess the severity of the potential impact, to include potential harm to organizational operations, assets, individuals, other organizations, or the nation.
  • Consider whether the ultimate risk may be sufficiently mitigated or whether it should be transferred, avoided, or accepted.

AI-related risks may include, among other things, technology failure, biased data, adversarial attacks, supply chain compromises, human error, cost overruns, legal compliance challenges, or oversight issues.

An initial risk level is determined by considering the likelihood of a failure against the severity of the potential impact. For example, is there is a low, moderate, or high likelihood of supply chain compromise? Would such a compromise affect only one discrete system or are there system-wide implications? These calculations will result in an initial risk level. Then potential mitigation measures, such as additional policies, training, or security measures, are applied to lower the initial risk level to an adjusted risk level. For example, physically or logically segmenting an organization’s systems so that a compromise only touches one system would significantly decrease the risk level associated with that particular technology. The higher the likelihood of supply chain compromise, the lower the severity of its impact must be to offset the risk, and vice versa. Organizations should apply the Swiss Cheese Model of more than one preventative or mitigative action for a more effective layered defense. Organizations then must consider the adjusted risk level in relation to their tolerance for risk; how much risk (and potential consequence) is acceptable in pursuit of value? This requires defining the IC’s risk tolerance levels, within which IC elements may again define their own levels based upon their unique missions.

Understanding and considering the risk of action is an important step forward for the IC, but it is not the last step. Sometimes overlooked in risk assessment practices is the consideration of the risk of inaction. To fully evaluate potential options, decision-makers must consider whether the overall risk of doing something is outweighed by the risks of not doing it. If the IC does not pursue particular AI capabilities, what is the opportunity cost of that inaction? Any final determination about whether to take action must consider whether declining to act would cause greater risk of significant harm. While the answer will not always be yes, in the case of AI and emerging technology, it is a very realistic possibility.

And, finally, a risk framework only works if people know about it. Broad communication – about the existence of the framework, how to apply it, and expectations for doing so – is vital. We cannot hold people accountable for appropriately managing risk if we do not clearly and consistently communicate and help people use the structure and mechanisms for doing so.

Buy-in To Enhance Confidence

An IC-wide AI risk framework will help IC officers understand risks and determine when and how to take advantage of innovative emerging technologies like AI, increasing comfort with uncertainty and risk-taking in the pursuit of new capabilities. Such a risk framework will have even greater impact if it is accepted – explicitly or implicitly – by the IC’s congressional overseers. The final article in this series will delve more deeply into needed changes to further improve the crucial relationship between the IC and its congressional overseers. It will also provide a link to a full report that provides more detail on each aspect of the series, including a draft IC AI Risk Framework.

Although Congress is not formally bound by such a framework, given the significant accountability measures that often flow from these overseers, a meeting of the minds between the IC and its congressional overseers is critical. Indeed, these overseers should have awareness of and an informal ability to provide feedback into the framework as it is being developed. This level of transparency and partnership would lead to at least two important benefits: first, increased confidence in the framework by all; and second, better insight into IC decision-making for IC overseers.

Ultimately, such a mutual understanding would encourage exactly what the IC needs to truly take advantage of next-generation technology like AI: a culture of experimentation, innovation, and creativity that sees reasonable risk and failure as necessary steps to game-changing outcomes.

Read also AI and the IC: The Tangled Web of Budget and Acquisition

Read also Artificial Intelligence in the IC: Culture is Critical

Read also AI and the IC: The Challenges Ahead

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For the first time since the start of the pandemic, the number of new daily Covid cases in Germany has exceeded 60,000, according to the country’s disease control and prevention agency, the Robert Koch Institute.

Authorities fear that in reality the figure is even higher, as not all cases are immediately reported or detected. Just a week ago, the number of daily infections across Germany surpassed the 50,000 mark.

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Among the country’s Covid hotspots are Thuringia, Saxony and Bavaria. In the latter region, hospitals are so overwhelmed with Covid patients that they have had to put off any non-emergency surgery.

Against this grim backdrop, lawmakers in the Bundestag on Thursday backed a new set of measures aimed at containing the spread of the disease. The package was proposed by Germany’s Social Democrats, the Green and Free Democratic parties, which are expected to form a new coalition government as early as next week.

If passed by the upper house, the rules would include mandatory daily Covid testing for employees of, and visitors to, care homes, regardless of vaccination status. Germans would also be required to show proof of full vaccination, recovery or a fresh negative Covid test in order to enter their workplace or use public transport.

On top of that, those caught selling and forging fake certificates and tests could face up to five years behind bars. Just like the Covid regulations currently in place, the new plan gives some leeway to regional authorities in terms of restrictions so that, for instance, the banning of recreational, cultural, and sporting events will be at their discretion. However, things like travel bans, curfews and massive closures of businesses would now be off-limits to local government.

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The stars of the Harry Potter films will reunite for a 20-year anniversary special on HBO, minus author JK Rowling. Fans and commenters wondered if Rowling’s absence had anything to do with her views on transgender issues.

‘Harry Potter and the Sorcerer’s Stone’ premiered 20 years ago this week, catapulting actors Daniel Radcliffe, Rupert Grint, and Emma Watson to superstardom. Warner Bros announced on Tuesday that the three stars – ​​as well as a whole range of supporting actors from the franchise – will travel back to Hogwarts for an “enchanting making-of story” airing on New Year’s Day, entitled ‘Harry Potter 20th Anniversary: Return to Hogwarts’. 

Conspicuously absent from the production is author JK Rowling. A Warner Bros’ press release made no mention of Rowling, and a lengthy Instagram post by actress Emma Watson thanked fans and fellow cast members, but also made no mention of Rowling, whom other Harry Potter actors said they “owe everything” to.

Rowling’s PR team did not comment on the author’s absence, and the Hollywood Reporter claimed that the author will only appear in the show in archival footage. 

Commentators online reckoned that Rowling had been canceled from the retrospective special due to her high-profile clashes with transgender activists. A self-described feminist, Rowling has spoken out against gender-neutral language, arguing that it “erases” the concept of sex and therefore the concept of womanhood. She has also stated that sex is a binary concept, and argued against gender-neutral bathrooms, claiming that by allowing men into women’s bathrooms, women are made less safe.

Rowling’s comments on gender issues generated intense backlash from LGBT organizations, and death and rape threats from the most zealous transgender ideologues online. Actors Daniel Radcliffe and Emma Watson also both spoke out against Rowling’s defense of biological sex last year, with Radcliffe declaring that “transgender women are women,” and apologizing to upset fans “for the pain [Rowling’s] comments have caused you.”

“Trans people are who they say they are and deserve to live their lives without being constantly questioned or told they aren’t who they say they are,” Watson chimed in.

Rowling has repeatedly stated that she is against anti-trans discrimination, but would not change her position on sex. “I refuse to bow down to a movement that I believe is doing demonstrable harm in seeking to erode ‘woman’ as a political and biological class and offering cover to predators like few before it,” she wrote last year.

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Japan’s fifth wave of Covid-19 has virtually disappeared so dramatically that some scientists are puzzled as to why it happened. One team suggests the highly infectious Delta strain mutated into extinction on the island nation.

In mid-August, Japan experienced a peak in Covid-19 infections, recording over 23,000 new cases per day. Now the metric is just around 170, with deaths attributed to the disease mostly remaining in single digits this month.

The decline has been attributed by many to high vaccination rates, public acceptance of masks, and other factors, but some researchers say the drop was uniquely significant, compared to other nations with similar conditions.

Ituro Inoue, a geneticist at the National Institute of Genetics, believes that Japan had the good fortune of witnessing the Delta strain mostly rooting out other variants of the SARS-CoV-2 virus before then eradicating itself. He explained his team’s theory to the Japan Times newspaper this week.

For some time now, Inoue and his fellow scientists were researching mutations of SARS-CoV-2 and how they are affected by the protein nsp14, which is crucial for the reproduction of the virus.

RNA viruses, like the one causing Covid-19, tend to have a very high mutation rate, which helps them quickly adapt to changes in the environment. However, this opens the door for a so-called “error catastrophe,” when bad mutations pile up and finally cause the full extinction of a strain. The protein nsp14 appears to offer a form of error proofreading that helps the virus genome to stay below the threshold of the “error catastrophe.”

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In the case of Japan’s fifth wave of Covid-19, the Delta variant’s nsp14 failed at this job, Inoue believes, based on the genetic study of specimens collected from June to October. Contrary to his team’s expectations, there was a lack of genetic diversity, while many samples had many genetic changes in the site called A394V, which is linked to the error-fixing protein.

“We were literally shocked to see the findings,” the researcher told the Japan Times. “The Delta variant in Japan was highly transmissible and [was] keeping other variants out. But as the mutations piled up, we believe it eventually became a faulty virus and it was unable to make copies of itself.”

The theory could be relevant to the previous SARS strain, which was identified in 2003, explaining why it didn’t cause a pandemic. But that would be hard to confirm, since the outbreak ended relatively quickly and didn’t result in the massive collection of genetic data necessary to test the hypothesis.

It’s not clear why Japan had this lucky turn of events, but nothing comparable happened in other East Asian countries like South Korea, where populations are genetically close to that of Japan. Virus mutations similar to those flagged by the scientists have been discovered in at least 24 countries, Inoue said. He and his team plan to publish a paper detailing their findings by the end of November.

Even if the natural extinction theory is confirmed, it is at best a temporary reprieve for the Japanese people. New, more successful strains are likely to eventually find their way into the country, though quarantine measures and immigration control could delay the emergence of new variants in Japan, Inoue believes.

Meanwhile, Tokyo is bracing for a new wave of Covid-19 this winter and is preparing to live with the virus. The government reportedly plans to ease travel restrictions by increasing the number of people it allows to enter the country per day from 3,500 to 5,000.

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