Japan’s fifth wave of Covid-19 has virtually disappeared so dramatically that some scientists are puzzled as to why it happened. One team suggests the highly infectious Delta strain mutated into extinction on the island nation.
In mid-August, Japan experienced a peak in Covid-19 infections, recording over 23,000 new cases per day. Now the metric is just around 170, with deaths attributed to the disease mostly remaining in single digits this month.
The decline has been attributed by many to high vaccination rates, public acceptance of masks, and other factors, but some researchers say the drop was uniquely significant, compared to other nations with similar conditions.
Ituro Inoue, a geneticist at the National Institute of Genetics, believes that Japan had the good fortune of witnessing the Delta strain mostly rooting out other variants of the SARS-CoV-2 virus before then eradicating itself. He explained his team’s theory to the Japan Times newspaper this week.
For some time now, Inoue and his fellow scientists were researching mutations of SARS-CoV-2 and how they are affected by the protein nsp14, which is crucial for the reproduction of the virus.
RNA viruses, like the one causing Covid-19, tend to have a very high mutation rate, which helps them quickly adapt to changes in the environment. However, this opens the door for a so-called “error catastrophe,” when bad mutations pile up and finally cause the full extinction of a strain. The protein nsp14 appears to offer a form of error proofreading that helps the virus genome to stay below the threshold of the “error catastrophe.”
In the case of Japan’s fifth wave of Covid-19, the Delta variant’s nsp14 failed at this job, Inoue believes, based on the genetic study of specimens collected from June to October. Contrary to his team’s expectations, there was a lack of genetic diversity, while many samples had many genetic changes in the site called A394V, which is linked to the error-fixing protein.
“We were literally shocked to see the findings,” the researcher told the Japan Times. “The Delta variant in Japan was highly transmissible and [was] keeping other variants out. But as the mutations piled up, we believe it eventually became a faulty virus and it was unable to make copies of itself.”
The theory could be relevant to the previous SARS strain, which was identified in 2003, explaining why it didn’t cause a pandemic. But that would be hard to confirm, since the outbreak ended relatively quickly and didn’t result in the massive collection of genetic data necessary to test the hypothesis.
It’s not clear why Japan had this lucky turn of events, but nothing comparable happened in other East Asian countries like South Korea, where populations are genetically close to that of Japan. Virus mutations similar to those flagged by the scientists have been discovered in at least 24 countries, Inoue said. He and his team plan to publish a paper detailing their findings by the end of November.
Even if the natural extinction theory is confirmed, it is at best a temporary reprieve for the Japanese people. New, more successful strains are likely to eventually find their way into the country, though quarantine measures and immigration control could delay the emergence of new variants in Japan, Inoue believes.
Meanwhile, Tokyo is bracing for a new wave of Covid-19 this winter and is preparing to live with the virus. The government reportedly plans to ease travel restrictions by increasing the number of people it allows to enter the country per day from 3,500 to 5,000.
Protests against renewed Covid-19 restrictions turned violent in The Hague. The unrest comes a day after several demonstrators in another Dutch city, Rotterdam, were injured amid police gunfire.
Seven people were arrested after fierce clashes broke out between law enforcement and anti-lockdown demonstrators in The Hague, the seat of the International Court of Justice (ICJ), on Saturday.
A video shared on social media shows protesters lighting firecrackers that sparked multiple fires, causing the skies in the city to glow an eerie red.
The Hague burns🔥, home of international court of justice, the seat of Dutch cabinet and 3rd largest city in Netherlands pic.twitter.com/8gjqu2sE60
Dutch police reported that five of its officers were injured in the showdown with rioters. One officer was taken to hospital with a knee injury and concussion. Two others “suffered hearing damage,” while another two suffered injuries to their hands.
The chaotic scenes in the Netherlands’ third-largest city unfolded a day after a protest against reimposed Covid-19 restrictions in Rotterdam was marred by violence. Over 50 people were arrested in the city and three were injured after police opened fire in a bid to quell the unrest. Police later claimed that officers were “compelled to shoot at targets” to protect themselves. The three injured protesters remain in hospital, and their condition is unknown.
Protests have swept through a number of Dutch cities after the Netherlands became the first country in Western Europe since summer to go into a partial lockdown last week. Tensions soared further after the government banned New Year’s Eve fireworks displays and the Dutch parliament backed the introduction of the so-called 2G system, which would bar the unvaccinated and those who have not recently recovered from the virus from a long list of public places if introduced.
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Palestinian Islamist group Hamas has called on Canadian singer Justin Bieber to cancel his upcoming concert in what it calls the “Zionist occupation state” of Israel.
Bieber announced his 2022 world tour dates this week, with a concert in Tel Aviv planned for next October. On Thursday, Hamas’ Artistic Production Department issued a statement, cited by the Palestinian Sawa news outlet, “condemning and denouncing” the performer. It called on the star to cancel the show and “boycott the Zionist occupation state in protest at its repeated crimes against the Palestinian people.”
Bieber has performed in Israel multiple times, his last performance there having been in 2017 at Park HaYarkon – the same venue slated for next year. Since the announcement of the ‘Justice’ tour dates, calls for him to cancel the Tel Aviv show have gained momentum across social media, with many posters condemning the singer for supporting what one called an “apartheid state.”
Some noted that Bieber was set to arrive in Israel after performing in South Africa. “Justin Bieber is really going straight from SA to Israel. From a country that fought apartheid to a country that’s practicing apartheid,” one Twitter user complained.
A petition asking the singer to boycott Israel and exclude it from his tour has been launched online, and had garnered some 3,700 signatures by Friday.
In 2018, the New Zealand singer Lorde canceled a concert in Israel, subsequently thanking fans for “educating” her on the issue, and, the same year, US artist Lana Del Rey at first defended her decision to perform in the country, saying her appearance would not be a “political statement,” before backtracking and canceling the gig.
Hamas has been designated a terrorist group by the US, the EU, and, as of Friday, the UK. In April 2021, international non-governmental organization Human Rights Watch concluded in a report that Israel had committed “crimes against humanity of apartheid and persecution.”
Despite COVID-19 lockdowns and restrictions, some 650,000 women and girls were provided with gender-based violence services through a joint UN and European Union (EU) programme working to stamp out what is arguably one of the most prevalent human rights violations.
Just three days after restrictions were announced for unvaccinated Austrians, a provincial governor is pressing for a nationwide lockdown of all residents as Covid-19 infections continue to hit record highs.
“If no national lockdown is ordered tomorrow, there will definitely have to be a lockdown of several weeks in Upper Austria, together with our neighboring province Salzburg as of next week,” Upper Austria Governor Thomas Stelzer told lawmakers on Thursday.
That will mean at least two of Austria’s nine provinces will be in full lockdown mode just days after the nation created a two-tier society by locking down approximately two million unvaccinated Austrians.
“We must raise the vaccination rate. It is shamefully low,” Chancellor Alexander Schallenberg said on Sunday, announcing that unvaccinated residents would only be allowed to leave their homes for “essential” purposes, such as to buy groceries or go to a doctor’s office.
Police are now doing random checks for proof of vaccination on Austrian streets. Those unvaccinated residents who are found to be in violation of the lockdown order face steep fines of up to €500. Those who refuse to go through a vaccination status check will have to pay about three times as much.
Stelzer and other Austrian governors are scheduled to meet with Schallenberg and Health Minister Wolfgang Mueckstein on Friday, when a full lockdown will likely be considered.
New Covid-19 cases in the country passed the 15,000 mark for the first time on Thursday, far surpassing 2020’s daily high of 9,586, set when no vaccines were available. Upper Austria and Salzburg have been hit the hardest, putting hospitals at risk of bed shortages. With some 66% of its population fully vaccinated, Austria lags behind other Western European countries in terms of the Covid-19 vaccination rate.
While Austria is the first to impose a lockdown on the unvaccinated, other EU countries – including Slovakia, the Czech Republic and Greece – have imposed increasingly tight restrictions on people who haven’t accepted a Covid vaccine.
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Syrian-born musician Omar Souleyman, who worked with the likes of Bjork and Damon Albarn, has been detained in Turkey over alleged links to the Kurdistan Workers’ Party, which is deemed a terrorist group by Ankara.
Souleyman was brought in for questioning on Wednesday, with officers also searching through his home in Turkey’s southeastern province of Sanliurfa, the singer’s manager said.
The arrest was likely provoked by recent reports that the musician had traveled to an area in Syria controlled by the Kurdish militias known as the YPG, he added.
The YPG have been US allies in the fight against Islamic State (IS, formerly ISIS), but Turkey considers them to be an extension of the Kurdistan Workers’ Party (PKK) and a threat to its national security.
For decades, the Workers’ Party has been fighting Turkish troops in the southeast of the country, striving for greater autonomy for the Kurdish population.
Souleyman’s son denied his father’s alleged terrorist links, saying he didn’t have any political affiliation and had become the victim of a “malicious report.” Some media outlets claimed the musician could be released from custody later on Thursday.
Coming from Syria’s majority-Kurdish province of Hasekeh, Souleyman had been known as a prolific wedding performer in his home country. But his international career skyrocketed after he moved to Turkey a decade ago, fleeing the Syrian conflict. The 55-year-old’s clips, including his top hit ‘Warni Warni’, have garnered millions of views on YouTube. He performed at the Nobel Peace Prize ceremony in 2013, as well as at many large festivals around the globe.
His unique style, which is based on mixing traditional Middle Eastern folk music with electronic sound, has attracted the attention of such stars as Bjork, Four Tet, Damon Albarn, and Diplo, who have all collaborated with Souleyman.
President Joe Biden commented on reports that US officials are planning to boycott the upcoming Olympics in Beijing over alleged human rights violations – but his answer left journalists perplexed.
When asked on Tuesday if an official US delegation will be traveling to the Winter Games in the Chinese capital in February, Biden responded: “I am the delegation.”
The president, however, did not elaborate, leaving the White House correspondents in a state of confusion, as his response could mean that Biden will attend the Winter Olympics alone or, as some reporters suggested, that he simply did not understand the question.
A recent report by a Washington Post columnist claimed the US won’t be sending an official delegation to Beijing in 2022 over allegations of human rights violations by the Chinese government. According to the sources cited in the article, a formal recommendation for a diplomatic boycott of the Olympics has been already presented to Biden, with the move expected to be approved by the president by the end of November.
The piece was published on the day that Biden held a lengthy virtual meeting with Chinese leader Xi Jinping, in which they discussed a range of issues regarding the strained relations between the two nations – but not the Olympics.
The White House said that during the talks, President Biden challenged his Chinese counterpart over what Washington sees as persecution against the Uyghur population in the Xinjiang region, as well as human rights violations in Tibet and Hong Kong. China has strongly denied the claims, accusing the US of interfering in its internal affairs.
Calls for the Biden administration to boycott the Olympics and refrain from sending a political delegation to Beijing have recently been made by top Democratic and Republican lawmakers.
If implemented, it won’t affect the American athletes, who will still be taking part in the Winter Olympics.
After vowing to retaliate against Lithuania’s move to allow Taiwan open a “representative office” in Vilnius, Beijing has announced it is downgrading diplomatic relations with the Baltic state.
In a statement on Sunday, the Chinese foreign ministry said that China’s diplomatic relations with Lithuania will be formally lowered to the level of charge d’affaires, while blasting Vilnius for setting a “bad international precedent” by giving the island the green light to open its mission in the Lithuanian capital.
The ministry went on to accuse Vilnius of undermining the One China principle and the principle of neutrality in bilateral relations, explaining its decision to demote relations by citing the need to “safeguard its sovereignty and the basic norms of international relations.”
“The Lithuanian government must bear all the consequences arising from this,” the ministry said, while calling on Vilnius to “correct its mistakes immediately.”
“No matter how the ‘Taiwan independence’ forces distort facts and reverse black and white, they cannot change the historical fact that the mainland and Taiwan belong to the same China,” the ministry asserted.
The move comes just two days after Beijing went on a verbal offensive against the Baltic country, warning that pushback for its cozying up to Taiwan would be imminent. “As to what necessary measures China will take, you may wait and see,” it said at the time.
Lithuania and China have been embroiled in a diplomatic row and have not maintained relations at ambassadorial level since September. After the Baltic state revealed that it would be opening a de facto Taiwanese embassy, China withdrew its ambassador from the country in August. Vilnius followed suit the following month.
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People around the world will need to get a jab against Covid-19 once a year, at least when it comes to the Pfizer vaccine, BioNTech’s CEO Ugur Sahin said in an interview on Sunday, as he praised the quality of its booster shot.
In an interview with Germany’s Bild newspaper on Sunday, Sahin said he considers the vaccine, co-developed by his company, to be “very effective.”
When asked whether people should be worried about the “breakthrough infections” – in which those vaccinated with the Pfizer-BioNTech vaccine still developed Covid-19 symptoms – he dismissed such concerns, saying that the jab offers a “90 percent protection” against cases that require intensive care in those aged over 60.
A “very high” level of protection against severe illness lasts for up to nine months, the BioNTech CEO maintained. He said this level starts decreasing “from the fourth month,” however. To maintain the protection, Sahin strongly pushed for booster shots, arguing that they would not just restore levels of antibodies but would potentially help “to break … chains of infection.”
He also encouraged doctors to be “as pragmatic as possible” when it comes to greenlighting vaccination and “not to send people home unvaccinated even though they could be vaccinated without any problems.”
In the future, people might need to get booster shots once a year, the BioNTech CEO believes. He said that he expects protection from a booster shot to “last longer” than the initial immunity one acquires after getting two doses of the vaccine.
“Subsequent … vaccinations may only be needed every year – just like [with] influenza,” he said. Currently, the German Federal Center for Health Education – an agency subordinated to the Health Ministry – recommends a booster shot six months after one gets the second dose of a vaccine. It also says that “booster vaccination makes sense after a minimum interval of about four months.”
Sahin’s interview comes days after it was revealed that Pfizer, BioNTech and Moderna are making a combined profit of $65,000 every minute – all thanks to their Covid-19 jabs. That is according to estimates made by the People’s Vaccine Alliance (PVA) – a coalition demanding wider access to vaccines.
The PVA estimated that the three companies are to earn a total of $34 billion in combined pre-tax profits this year alone, which roughly translates into more than $1,000 a second and $93.5 million a day.
PVA has slammed the three companies over their refusal to allow vaccine technology transfer despite receiving a combined $8 billion in public funding. Such a move could increase global supply and save millions of lives as well as drive down prices, the coalition said.
“Pfizer, BioNTech and Moderna have used their monopolies to prioritize the most profitable contracts with the richest governments, leaving low-income countries out in the cold,” said Maaza Seyoum of the African Alliance and People’s Vaccine Alliance Africa.
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