For the first time since the start of the pandemic, the number of new daily Covid cases in Germany has exceeded 60,000, according to the country’s disease control and prevention agency, the Robert Koch Institute.
Authorities fear that in reality the figure is even higher, as not all cases are immediately reported or detected. Just a week ago, the number of daily infections across Germany surpassed the 50,000 mark.
Among the country’s Covid hotspots are Thuringia, Saxony and Bavaria. In the latter region, hospitals are so overwhelmed with Covid patients that they have had to put off any non-emergency surgery.
Against this grim backdrop, lawmakers in the Bundestag on Thursday backed a new set of measures aimed at containing the spread of the disease. The package was proposed by Germany’s Social Democrats, the Green and Free Democratic parties, which are expected to form a new coalition government as early as next week.
If passed by the upper house, the rules would include mandatory daily Covid testing for employees of, and visitors to, care homes, regardless of vaccination status. Germans would also be required to show proof of full vaccination, recovery or a fresh negative Covid test in order to enter their workplace or use public transport.
On top of that, those caught selling and forging fake certificates and tests could face up to five years behind bars. Just like the Covid regulations currently in place, the new plan gives some leeway to regional authorities in terms of restrictions so that, for instance, the banning of recreational, cultural, and sporting events will be at their discretion. However, things like travel bans, curfews and massive closures of businesses would now be off-limits to local government.
A gunman injured two civilians, one of them fatally, and two police officers before being shot dead by security forces near Jerusalem’s Western Wall on Sunday morning, Israeli police said.
The civilian victims were taken to Shaare Zedek Medical Center. One, who was in his 30s, succumbed to his injuries at the hospital. The other, a 46-year-old, is said to have suffered moderate injuries. Two police officers were hurt by shrapnel.
Two civilians were critically and seriously wounded this morning, Sunday, and two policemen were lightly wounded in a shooting attack in the area of the Chain Gate near the Western Wall and the entrance to the Temple Mount. pic.twitter.com/MRN6MLckj3
In a video clip shared on social media and purportedly filmed at the scene, multiple gunshots could be heard amid agitated shouting. Security officers could then be seen standing around what appears to be a dead body. Witnesses speculated it was that of a “terrorist.”
Scenes and sounds of shooting in the Old City of Jerusalem captured on Live Cam. Initial reports are attack is near the Temple Mount area 2 Israelis wounded one apparently seriously the terrorist has been neutralised pic.twitter.com/UKWSOqCu8D
— ElBluemountain MossadDolphin 🇮🇱🐬🇮🇱🐬🇮🇱 (@EBluemountain1) November 21, 2021
The gunman, whose identity was not immediately disclosed, was killed during the incident. Police said he had used a homemade submachine gun.
AstraZeneca has announced that its preventative antibody cocktail offers 83% protection against symptomatic Covid-19 for at least six months, making it more effective than its own vaccine.
In a statement on Thursday, AstraZeneca cemented its lead in the race to develop and market a preventative Covid-19 drug, which is delivered as a shot in the arm.
The drug, named AZD7442, reduces the risk of symptomatic Covid-19 by 83% over the course of six months, according to data from a trial in which participants were given one 300mg dose. There were no deaths or severe infections recorded within the trial group, it said.
A separate trial showed the drug reduced the risk of severe Covid-19 or death by 88% when administered within three days of the onset of symptoms.
“These new data add to the growing body of evidence supporting AZD7442’s potential … We are progressing regulatory filings around the world and look forward to providing an important new option against SARS-CoV-2 [Covid-19] as quickly as possible,” AstraZeneca Executive Vice President Mene Pangalos said in the statement.
The Anglo-Swedish firm has agreed to supply the US government with 700,000 doses of AZD7442 if the Food and Drug Administration grants it emergency use, which AstraZeneca requested on October 5. The firm has similar agreements with other nations.
The drug is created using a combination of two antibodies originating from immune B-cells donated by a recovering Covid-19 patient.
The treatment could be used in people who are known not to respond well to vaccines, such as cancer patients. Around 2% of people are considered to be at risk of not creating enough antibodies following the administration of a Covid-19 vaccine.
Based on the numbers, the drug appears to be more effective than the firm’s first-generation Covid-19 vaccine. Britain’s Zoe Covid study showed the effectiveness of the vaccine dropped to around 67% after four to five months.
As infections are rising again, scientists all around the world are rushing to fight the danger, offering a choice of new treatments and unusual variants of vaccines.
Levels of contagion are setting new records, hospitals are overwhelmed, governments are starting to introduce lockdowns, and not only for unvaccinated people – the picture of the fight against Covid-19 looks quite disappointing. However, there’s still a place for good news: Research teams report positive results while trialling new medicines and vaccine types.
Nasal vaccines
Vaccination will remain one of the most effective tools against Covid-19. As Professor David Dockrell, from the Center for Inflammation Research of the University of Edinburgh, told RT, “vaccines will continue to be a central part of how we control the virus.”
“If we can dampen down the number of infections, and the severity of infections, and also the extent to which the virus can replicate in people when they become infected, then we are slowing down the ability of the virus to change and to mutate,” he explains.
So I think the vaccines still will be a very important part of the preventive strategy. It’s vital that they are available to all the world’s population, irrespective of where people live, and the wealth of the country in which they live.
However, vaccination doesn’t always mean you have to get an injection. For instance, several intranasal Covid-19 vaccines are currently being developed. As the virus gets into the body through the nose, a nasal spray or drops are aimed to produce mucosal immune response and prevent it from getting into the lungs.
In India, a vaccine of this type is already completing Phase 2 of clinical trials. In Russia, a nasal vaccine is undergoing a clinical trial on volunteers. In Thailand, a home-developed product is expected to be trialed on humans next spring. In the US, Universities of Houston and Stanford recently reported good results of their experiments carried out on mice.
Intranasal vaccines can have several potential benefits compared to inoculation.
“They would be easier to use, because they can be self-administered. They wouldn’t need a nurse or clinical settings,” Swedish professor emeritus of epidemiology Marcello Ferrada de Noli explained to RT. As a result, he says, there’s hope that fewer people will be reluctant to be immunized. Not so many of us find it pleasant to get a jab – and after all, there are those who are just afraid of needles. Also, it would be much easier to vaccinate children with nasal substances.
However, what concerns Prof. de Noli the most is the duration of the effect of a vaccine of this type. Still, scientists can’t say for sure whether a nasal substance may completely replace a shot. According to Alexander Gintsburg, the head of Moscow’s Gamaleya Center biomedical research institute, which created the Sputnik V vaccine, the nasal version they are working on would serve for an additional protection against the virus, but would not replace the injections.
Chew the virus away?
A nasal vaccine is not the only one being developed. In summer, it was revealed that Russian Defense Ministry scientists were creating a ‘chewing gum’ vaccine, also targeting the mucosal immune response. Meanwhile, a UK firm announced this month that it would conduct a human trial of a skin patch that uses T-cells to confront the virus. Developers hope it would offer longer-lasting immunity than the existing vaccines. Work on a similar project is being done in the University of Queensland, Australia.
While it all looks so promising, Prof. de Noli warns that it would still take a lot of time until these products become available to the public. “I think that discoveries in this field are a very good thing. But if we say ‘We discovered a new type of vaccine’, people will say ‘Aha, so I’m going to wait’. But we need to vaccinate people now,” he points out.
Improving Covid treatment
Vaccines are not a silver bullet, unfortunately, given the not-so-high level of global immunization and the constantly emerging new strains of the virus. “People might get infected despite having had a vaccine, but I still think the vaccine strategy is going to be central to how we manage this kind of virus going forward,” Prof. Dockrell says. “But we will have other strategies that will be very important. We will have other elements. When we put them all together, it gives us the best opportunity that people can live with coronaviruses, and hopefully, the mortality can be limited to much lower extense than what we’ve sadly seen in the last eighteen months.”
Monoclonal antibodies will be central to the ongoing vaccine strategy, Prof. Dockrell explains. These are the antibodies similar to those the body uses to fight the virus. They are produced in labs and given via infusion or injection to boost the patient’s response against certain diseases. Monoclonal antibody treatment is used for people under a high risk of developing severe infection (including older patients 65+ years old or those with chronic medical conditions). It’s already being used in the US, following last year’s FDA approval. Earlier in November, the European Medicines agency recommended authorizing two monoclonal antibody medicines.
In October, UK’s AstraZeneca reported positive results of a Phase 3 study of its antibody combination, which, according to developers, is highly effective in both prevention and treatment of coronavirus.
Researchers are also working on a possibility to save Covid-infected patients from the so-called ‘cytokine storm’ – a situation when the immune system reacts so intensely that kills not only the virus, but the whole organism itself. A drug to ‘calm the storm’ was registered in Russia this year, and it’s already being used on patients.
Another way to fight Covid-19 is to use antiviral drugs. When the pandemic started, medics had to use something already existing (like anti-influenza Favipiravir) or something being authorized for emergency use (like remdesivir). Now, more than a year on, the work to create a special drug to specifically cure Covid-19 is giving its results. This month, Russia registered its first injectable anti-Covid medicine. A bit earlier, the UK became the first country to approve an antiviral pill produced by the US-based companies Merck and Ridgeback Biotherapeutics. Another American firm, Pfizer, got positive results from trials of its drug of the same kind. Both firms hope that with a drug in the form of a pill it would be easier to treat people at home.
Appreciating all the efforts on the field of developing anti-Covid treatment, Prof. de Noli points out that still, the key issue now is to reduce the spreading of the virus. “The new medicines are developed for people who already got the disease,” he says.
But we need to prevent people from getting the infection, not let them get infected because we have some new medicine that can cure them.
The same idea is echoed by scientists all over the world quoted in plenty of articles dedicated to the medical gains: it’s great to have the treatment, but none of the drugs may substitute vaccination, as first and foremost, humanity has to adopt preventive measures and stop the pandemic.
People are weird. They cook and eat the strangest things. This time it’s an octopus stuffed inside a turkey, sitting on top of crab legs, and (optionally) garnished with bacon strips. This monstrous culinary invention was inspired by H.P. Lovecraft’s Cthulhu mythos, and honestly… it looks like a crime against food.
If this gallery wasn’t disgusting enough for you, you should also check out pre-cooked canned chicken that we’ve previously featured on this fun and useful site. We know you’ll love it!
The French government has kicked off a €14 million national campaign to tackle underage prostitution and pimping. It comes months after a report found as many as 10,000 youngsters, mostly teen girls, are involved in the sex trade.
The campaign, launched by the Ministry for Solidarity and Health on Monday, is expected to be fully rolled out in 2022. The ministry described the problem as a “growing phenomenon that society can no longer ignore” and about which “too little is known.”
The government programme is expected to “increase awareness” while helping to “inform and provide a better understanding of the phenomenon.” It also aims to help “identify the young people involved” and “prosecute clients and pimps more effectively.”
According to RFI, the prevalence of underage prostitution has increased by as much as 70% over the past five years, with social media believed to be compounding the problem. The public broadcaster noted that the situation had worsened during the Covid-19 pandemic when young people spent more time online.
In July, a working group produced a damning report that found between 7,000 and 10,000 young people were involved in prostitution across the country. The majority are young girls aged between 15 and 17, but a ministry statement noted that the “entry point” into prostitution was increasingly becoming younger at around 14-15 years.
“There’s really a normalisation of prostitution of young people because girls say that selling sex is a way of making lots of money easily and that it can help them reach their dream life,” deputy public prosecutor Raphaelle Wach told the news outlet France 24.
In its statement, the ministry noted that many minors did not consider themselves victims and valued the “financial autonomy” and feelings of “belonging to a group” and “regaining control” over their lives.
“These minors are however in danger, both physically and psychologically,” the ministry warned.
“Covid played a considerable role because social networking provided new ways of being able to hook in underage girls very easily,” Geneviève Collas, who runs an NGO fighting human trafficking, told RFI. She added that recruiting minors has been made “easier” with short-term apartment rental apps like Airbnb helping mask the scale of the problem on the streets.
The EU must quickly seal its external borders to stem the flow of migrants who are no longer welcome in the 27-member bloc, according to Slovenia’s interior minister, whose country currently holds the presidency of the EU Council.
Speaking at the ‘Sarajevo Migration Dialogue’ on Thursday, Interior Minister Ales Hojs said EU countries were preoccupied recently with the coronavirus pandemic, the fall of the government in Afghanistan, and now a migrant crisis on the Poland-Belarus border, which he said was a hybrid war waged by Minsk against the EU.
“All three have additionally contributed to the increase in numbers of illegal migrants moving towards Europe and the Balkans, destabilizing the European Union,” Hojs told reporters.
The Slovenian minister said the current situation was similar to the 2015 influx of refugees and migrants from the Middle East and North Africa, when the EU admitted over one million people across its borders.
This time the situation is different, Hojs said, warning that “there is no more ‘refugees welcome.’”
“I believe that external borders must be secured, even with fences if necessary,” Hojs said, saying that he supported a plan for Brussels to finance the building of fences to reinforce the bloc’s borders.
He said it was important to strengthen cooperation and partnership across the EU in order to better manage migration and maintain security.
Thousands of migrants have been trying to cross the Belarus-Poland border in an attempt to reach the EU. They have been stranded at barbed-wire fencing with Polish border guards repelling their attempts to cross. Warsaw has accused Belarus of orchestrating the crisis to destabilize the EU and “weaponize” migration in an effort to have sanctions lifted.
A spokesperson for Belarusian leader Alexander Lukashenko claimed on Thursday that Germany agreed to open a humanitarian corridor for 2,000 refugees on the border.
Japan’s fifth wave of Covid-19 has virtually disappeared so dramatically that some scientists are puzzled as to why it happened. One team suggests the highly infectious Delta strain mutated into extinction on the island nation.
In mid-August, Japan experienced a peak in Covid-19 infections, recording over 23,000 new cases per day. Now the metric is just around 170, with deaths attributed to the disease mostly remaining in single digits this month.
The decline has been attributed by many to high vaccination rates, public acceptance of masks, and other factors, but some researchers say the drop was uniquely significant, compared to other nations with similar conditions.
Ituro Inoue, a geneticist at the National Institute of Genetics, believes that Japan had the good fortune of witnessing the Delta strain mostly rooting out other variants of the SARS-CoV-2 virus before then eradicating itself. He explained his team’s theory to the Japan Times newspaper this week.
For some time now, Inoue and his fellow scientists were researching mutations of SARS-CoV-2 and how they are affected by the protein nsp14, which is crucial for the reproduction of the virus.
RNA viruses, like the one causing Covid-19, tend to have a very high mutation rate, which helps them quickly adapt to changes in the environment. However, this opens the door for a so-called “error catastrophe,” when bad mutations pile up and finally cause the full extinction of a strain. The protein nsp14 appears to offer a form of error proofreading that helps the virus genome to stay below the threshold of the “error catastrophe.”
In the case of Japan’s fifth wave of Covid-19, the Delta variant’s nsp14 failed at this job, Inoue believes, based on the genetic study of specimens collected from June to October. Contrary to his team’s expectations, there was a lack of genetic diversity, while many samples had many genetic changes in the site called A394V, which is linked to the error-fixing protein.
“We were literally shocked to see the findings,” the researcher told the Japan Times. “The Delta variant in Japan was highly transmissible and [was] keeping other variants out. But as the mutations piled up, we believe it eventually became a faulty virus and it was unable to make copies of itself.”
The theory could be relevant to the previous SARS strain, which was identified in 2003, explaining why it didn’t cause a pandemic. But that would be hard to confirm, since the outbreak ended relatively quickly and didn’t result in the massive collection of genetic data necessary to test the hypothesis.
It’s not clear why Japan had this lucky turn of events, but nothing comparable happened in other East Asian countries like South Korea, where populations are genetically close to that of Japan. Virus mutations similar to those flagged by the scientists have been discovered in at least 24 countries, Inoue said. He and his team plan to publish a paper detailing their findings by the end of November.
Even if the natural extinction theory is confirmed, it is at best a temporary reprieve for the Japanese people. New, more successful strains are likely to eventually find their way into the country, though quarantine measures and immigration control could delay the emergence of new variants in Japan, Inoue believes.
Meanwhile, Tokyo is bracing for a new wave of Covid-19 this winter and is preparing to live with the virus. The government reportedly plans to ease travel restrictions by increasing the number of people it allows to enter the country per day from 3,500 to 5,000.
Once you’ve reached optimal cat lady status, there comes a time in your life where you think it’s necessary to start massaging your cat’s head. Luckily, someone has already created a cat head massager, and it is most likely the most specific niche product you could think of. You can get it on Amazon or AliExpress.
If your cat didn’t love you before, rest assured he will love you now. Your cat will be so thankful for the head massage that he might even ignore you for less time throughout the day, and if you’re really lucky, your cat may even acknowledge your existence. …Or you can use it on yourself if you have a particularly small head.
In case you feel like you should have this thing in your (and your cat’s) life, you can get it on Amazon or AliExpress.
A pack of wild boars were rounded up and euthanized after one of the animals attacked a police officer in the streets of Hong Kong – the opening shot in a pitched battle between the feral hogs and the city’s law enforcement.
A group of veterinarians took seven wild boars into custody, euthanizing the beasts after knocking them out with dart guns in an area near the financial center of the city, according to a statement from Hong Kong’s Agriculture, Fisheries, and Conservation Department on Thursday.
The pigs were captured after one attacked a police officer last week, an act which reflects the city’s new policy toward the animals: stop them before they attack again.
The aggressive boar knocked down a police officer by biting his leg last week as the two faced off in a residential car park, the pig only losing the battle after falling off the building to its death. The wild boars are apparently “accustomed” to wandering back and forth along the roadway, begging for food from pedestrians and vehicles alike. Previously, the city had handled the population by capturing and sedating the animals, then relocating them to “remote areas,” according to the the department.
Hong Kong CEO Carrie Lam vowed to increase penalties for those citizens found feeding the boars, which have reportedly been responsible for some 30 attacks in recent years. While residents are warned not to feed the boars so as not to encourage population growth or disease outbreaks, the animals are a favorite among some visitors. Still, Lam insisted “we can’t simply sit on our hands while things deteriorate.”
Animal rights groups have responded with a protest letter against a policy of euthanasia, pointing out that most visitors do not feed the boars and arguing resources should be directed toward stopping the human activity rather than blaming all the boars. Allowing the boars to be captured and killed “ignores their right to live and considers their existence in urban areas as a capital offense,” the letter read.
