The EU’s drug regulator has backed the emergency use of Merck’s pill for the treatment for clinically vulnerable Covid-19 patients as cases surge across the continent.
On Friday, the European Medicines Agency (EMA) “issued advice” backing the emergency use of the drug developed by Merck in collaboration with Ridgeback Biotherapeutics, although it has not yet been authorized by national authorities.
In a statement, the drug regulator said the medicine called Lagevrio – also known as molnupiravir or MK 4482 – “can be used to treat adults with Covid-19 who do not require supplemental oxygen and who are at increased risk of developing severe Covid-19.”
It said the treatment should be administered as soon as possible after Covid-19 is diagnosed and within five days of the start of symptoms. The medicine should be taken twice a day for a period of five days.
The EMA listed the potential side effects of the capsules, including mild or moderate diarrhea, nausea, dizziness and headache. The treatment is not recommended for pregnant women.
The watchdog announced earlier on Friday that it had begun reviewing Pfizer’s medicine Paxlovid for Covid-19 with the same goal “to support national authorities” who may decide on its early use prior to marketing authorization in light of rising cases and deaths in Europe.
On Friday, Austria announced it would enter a new nationwide lockdown from Monday and make vaccination mandatory, while Germany’s health authorities claimed the country had turned into “one big outbreak.”
Both Pfizer and Merck have requested approval for their coronavirus medicines from the US Food and Drug Administration, but it is unclear when it might be granted.
Think your friends would be interested? Share this story!
An official inquiry has found that Germany’s justice system was staffed with former Nazis for decades after the Second World War, At one point, three out of four top officials at the prosecutor’s office were former party members.
Released on Thursday, the 600-page report was compiled by historian Friedrich Kiessling and legal scholar Christoph Safferling, and covers the Cold War period running from the early 1950s until 1974. The work was commissioned by the federal prosecutor’s office.
The researchers found that, at one point during the 1950s, roughly three in four top officials in the federal prosecutor’s office had been members of the Nazi Party. It took until 1972 before former Nazis were no longer in the majority in that office, and until 1992 before the judicial system had been fully purged of ex-members of the fascist party.
“There was no break, let alone a conscious break, with the Nazi past,” the researchers said of the situation.
Presenting the inquiry’s findings, state secretary at the justice ministry Margaretha Sudhof said the country has “long remained blind” to the presence of ex-Nazis in senior positions after the end of the Second World War.
“On the face of it they were highly competent lawyers… but that came against the backdrop of the death sentences and race laws in which they were involved,” Sudhof commented.
In a statement about the study’s publication, Justice Minister Christine Lambrecht said she welcomed “the fact that the Federal Prosecutor’s Office is also grappling with its troubled past and is shedding more light on its own Nazi entanglements in the post-war period.”
The federal prosecutor’s office is Germany’s highest prosecutorial authority, responsible for pursuing those who violate international law and commit alleged crimes relating to state security.
The latest study follows an earlier report published in 2016, which stated that in 1957 – more than a decade after the war had ended – 77% of senior officials in the justice ministry were former Nazis. At the time of that publication, then-Justice Minister Heiko Maas stated that the “Nazi-era lawyers went on to cover up old injustice rather than to uncover it, and thereby created new injustice.”
Syrian-born musician Omar Souleyman, who worked with the likes of Bjork and Damon Albarn, has been detained in Turkey over alleged links to the Kurdistan Workers’ Party, which is deemed a terrorist group by Ankara.
Souleyman was brought in for questioning on Wednesday, with officers also searching through his home in Turkey’s southeastern province of Sanliurfa, the singer’s manager said.
The arrest was likely provoked by recent reports that the musician had traveled to an area in Syria controlled by the Kurdish militias known as the YPG, he added.
The YPG have been US allies in the fight against Islamic State (IS, formerly ISIS), but Turkey considers them to be an extension of the Kurdistan Workers’ Party (PKK) and a threat to its national security.
For decades, the Workers’ Party has been fighting Turkish troops in the southeast of the country, striving for greater autonomy for the Kurdish population.
Souleyman’s son denied his father’s alleged terrorist links, saying he didn’t have any political affiliation and had become the victim of a “malicious report.” Some media outlets claimed the musician could be released from custody later on Thursday.
Coming from Syria’s majority-Kurdish province of Hasekeh, Souleyman had been known as a prolific wedding performer in his home country. But his international career skyrocketed after he moved to Turkey a decade ago, fleeing the Syrian conflict. The 55-year-old’s clips, including his top hit ‘Warni Warni’, have garnered millions of views on YouTube. He performed at the Nobel Peace Prize ceremony in 2013, as well as at many large festivals around the globe.
His unique style, which is based on mixing traditional Middle Eastern folk music with electronic sound, has attracted the attention of such stars as Bjork, Four Tet, Damon Albarn, and Diplo, who have all collaborated with Souleyman.
