The EU’s drug regulator has backed the emergency use of Merck’s pill for the treatment for clinically vulnerable Covid-19 patients as cases surge across the continent.
On Friday, the European Medicines Agency (EMA) “issued advice” backing the emergency use of the drug developed by Merck in collaboration with Ridgeback Biotherapeutics, although it has not yet been authorized by national authorities.
In a statement, the drug regulator said the medicine called Lagevrio – also known as molnupiravir or MK 4482 – “can be used to treat adults with Covid-19 who do not require supplemental oxygen and who are at increased risk of developing severe Covid-19.”
It said the treatment should be administered as soon as possible after Covid-19 is diagnosed and within five days of the start of symptoms. The medicine should be taken twice a day for a period of five days.
The EMA listed the potential side effects of the capsules, including mild or moderate diarrhea, nausea, dizziness and headache. The treatment is not recommended for pregnant women.
The watchdog announced earlier on Friday that it had begun reviewing Pfizer’s medicine Paxlovid for Covid-19 with the same goal “to support national authorities” who may decide on its early use prior to marketing authorization in light of rising cases and deaths in Europe.
On Friday, Austria announced it would enter a new nationwide lockdown from Monday and make vaccination mandatory, while Germany’s health authorities claimed the country had turned into “one big outbreak.”
Both Pfizer and Merck have requested approval for their coronavirus medicines from the US Food and Drug Administration, but it is unclear when it might be granted.
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American billionaire Bill Gates has claimed Covid-19 deaths and infections may drop below seasonal flu levels next year as more people get vaccinated and treatment improves, unless we encounter a new, more deadly variant.
Speaking on Thursday in a virtual interview at the Bloomberg New Economy Forum in Singapore, founder of Microsoft stated that vaccines, natural immunity and emerging oral treatments mean that “the death rate and the disease rate ought to be coming down pretty dramatically.”
The tech mogul, who has been particularly vocal during the pandemic, said issues around vaccine-production capacity are likely to be replaced by distribution challenges and even waning demand.
“The vaccines are very good news, and the supply constraints will be largely solved as we get out in the middle of next year, and so we’ll be limited by the logistics and the demand,” he noted.
He also told his audience that it remains to be seen how much demand there is for Covid-19 shots in places like Sub-Saharan Africa.
Calling for more work to eradicate flu, Gates claimed Covid-19 rates and deaths would possibly fall below those of flu by the middle of next year, unless more deadly coronavirus variants emerge.
The Bill and Melinda Gates Foundation has involved itself in the development of vaccines and virus surveillance, calling for a global response to the Covid-19 pandemic. The foundation has invested hundreds of millions dollars in the development and distribution of potentially lifesaving shots.
According to the World Health Organization, influenza kills up to 650,000 people each year. At least five million people have died from Covid-19 since the pandemic began in late 2019.
EXPERT PERSPECTIVE — On 16 June, US President Joe Biden and Russian President Vladimir Putin met for just under four hours in Geneva. This was Mr. Biden’s first meeting with Mr. Putin during his presidency and Biden is the fifth US President with whom Putin has held a summit.
Expectations for the summit were characterized as low by both sides in advance and assessed a bit more positively after the conclusion of the meeting. The meeting presented an opportunity for both leaders to present grievances and warnings to the other (and show toughness to their domestic constituencies). Other than presenting the opportunity to blow off steam, the results of the meeting appear modest: the agreement to return ambassadors to their posts, to resume bilateral arms control discussions, to conduct discussions on “strategic stability” and to hold unspecified consultations on cyber. In typical fashion, Mr. Putin rejected all of Mr. Biden’s assertions about Russian actions and made counter accusations referencing hostile US actions.
Of the deliverables from the summit, cyber will no doubt turn out to be the most problematic area for follow up. Mr. Biden apparently delivered to Mr. Putin a list of 16 US critical infrastructure sectors that should be considered “off limits” for cyberattacks, e.g., “red lines” not to be crossed without the risk of significant retaliation. For his part, Mr. Putin asserted that it is Russia that is the victim of cyberattacks originating from the territory of the US and it’s NATO partners and also is the victim of attempts to interfere with Russian elections. The challenge in cyber discussions going forward will center around three areas: differing interpretations of the relevance of deterrence theory in today’s cyber environment, attribution, and control.
Mr. Biden’s firm comments to Mr. Putin on recent cyberattacks against the US such as the ransomware attack on Colonial Pipelines (Mr. Biden is said to have asked Mr. Putin how he would react if Russia’s pipelines were hit?) and his provision of a list of “off limits” US infrastructure entities suggests a deep belief in this administration that Russia can be deterred from engaging in future conduct of cyber operations against US targets or “sanctioning” attacks originating from the territory of the Russian Federation by criminal groups.
Unfortunately, it is highly likely that either Mr. Putin nor those who control the levers of Russian cyber operations agree that deterrence theory applies. Deterrence only works when both sides know the other is capable of – and willing to – cause significant harm to the other.
The Russian side likely believes (and may have amply demonstrated) that the US is disproportionately vulnerable to cyber risk at every level of its economic, societal, and political infrastructure whereas Russia is not. There is a reason the use of cyber tools has become a central feature of Russian strategic doctrine. They work and seem a legitimate tool that falls short of conventional war. Hybrid warfare using cyber tools, the Russian side would argue, is no different than the economic warfare Russia is experiencing from sanctions imposed by the US its allies.
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Despite COVID-19 lockdowns and restrictions, some 650,000 women and girls were provided with gender-based violence services through a joint UN and European Union (EU) programme working to stamp out what is arguably one of the most prevalent human rights violations.
Czechia will prohibit people who have not been vaccinated from entering public spaces such as restaurants and shops from Monday. Negative Covid-19 tests will no longer be allowed.
Speaking on Wednesday, outgoing Prime Minister Andrej Babis said the country would adopt the so-called Bavarian model from Monday next week, prohibiting those who have not received a Covid-19 vaccine from entering public places. Those who have recently recovered from the virus will be allowed entry.
The country will enter a partial lockdown of the unvaccinated from Monday morning, assuming the restrictions are approved by the cabinet on Thursday.
“We will introduce the Bavarian model from Sunday to Monday. This means that entry to restaurants, service establishments, or mass events will only be allowed for vaccinated or survivors. Those vaccinated with a single dose must have a PCR test,” Babis said on local TV.
The prime minister said that self-testing would be completely cancelled, as he lamented unvaccinated people for clogging up hospitals and preventing treatment reaching those with other illnesses.
“The death toll is rising; the situation is serious. Vaccination is the only solution, there is no other,” he added.
The country is seeing a spike in infections, with a record 22,479 new cases reported on Tuesday.
The Bavarian model refers to strict anti-Covid measures introduced in the southern German state. Markus Soder, the state’s premier, claimed there was no choice but to implement “a kind of lockdown for the unvaccinated,” citing increasing pressure on hospitals and medical staff.
Meanwhile, some two million people in Austria who are yet to receive their Covid shots have been subject to the world’s first lockdown for the unvaccinated, in an effort to bring case numbers down.
While 68% of people are vaccinated in Germany, and 65% in Austria, just over 60% are vaccinated in the Czech Republic.
The children of families who were affected by the massive earthquake which devastated large parts of south-west Haiti in August this year are receiving free hot meals at school as part of an initiative by the UN’s World Food Programme (WFP) to support the recovery of the country’s most vulnerable communities.
People are weird. They cook and eat the strangest things. This time it’s an octopus stuffed inside a turkey, sitting on top of crab legs, and (optionally) garnished with bacon strips. This monstrous culinary invention was inspired by H.P. Lovecraft’s Cthulhu mythos, and honestly… it looks like a crime against food.
If this gallery wasn’t disgusting enough for you, you should also check out pre-cooked canned chicken that we’ve previously featured on this fun and useful site. We know you’ll love it!
The stars of the Harry Potter films will reunite for a 20-year anniversary special on HBO, minus author JK Rowling. Fans and commenters wondered if Rowling’s absence had anything to do with her views on transgender issues.
‘Harry Potter and the Sorcerer’s Stone’ premiered 20 years ago this week, catapulting actors Daniel Radcliffe, Rupert Grint, and Emma Watson to superstardom. Warner Bros announced on Tuesday that the three stars – as well as a whole range of supporting actors from the franchise – will travel back to Hogwarts for an “enchanting making-of story” airing on New Year’s Day, entitled ‘Harry Potter 20th Anniversary: Return to Hogwarts’.
Conspicuously absent from the production is author JK Rowling. A Warner Bros’ press release made no mention of Rowling, and a lengthy Instagram post by actress Emma Watson thanked fans and fellow cast members, but also made no mention of Rowling, whom other Harry Potter actors said they “owe everything” to.
Rowling’s PR team did not comment on the author’s absence, and the Hollywood Reporter claimed that the author will only appear in the show in archival footage.
Commentators online reckoned that Rowling had been canceled from the retrospective special due to her high-profile clashes with transgender activists. A self-described feminist, Rowling has spoken out against gender-neutral language, arguing that it “erases” the concept of sex and therefore the concept of womanhood. She has also stated that sex is a binary concept, and argued against gender-neutral bathrooms, claiming that by allowing men into women’s bathrooms, women are made less safe.
If I owed my entire career to 1 person, if I’d known her since I was 8, if I was worth $90m because of her, then not only would I defend her when maligned but I would refuse to take part in any reunion that excluded her. But that’s just me. #JKRowlinghttps://t.co/0ay5mhQ1FE
I can’t believe they’re actually shunning JK Rowling
“No you can’t participate in something celebrating the world you made because we are the new Amish but with more Puritan soul and no redeeming features”.
Rowling’s comments on gender issues generated intense backlash from LGBT organizations, and death and rape threats from the most zealous transgender ideologues online. Actors Daniel Radcliffe and Emma Watson also both spoke out against Rowling’s defense of biological sex last year, with Radcliffe declaring that “transgender women are women,” and apologizing to upset fans “for the pain [Rowling’s] comments have caused you.”
“Trans people are who they say they are and deserve to live their lives without being constantly questioned or told they aren’t who they say they are,” Watson chimed in.
Rowling has repeatedly stated that she is against anti-trans discrimination, but would not change her position on sex. “I refuse to bow down to a movement that I believe is doing demonstrable harm in seeking to erode ‘woman’ as a political and biological class and offering cover to predators like few before it,” she wrote last year.
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An object lurking in the outer region of our solar system may well be the elusive Planet 9, a leading British astronomer has suggested after digging through the telescope archives of 250,000 point sources.
Possible evidence of a mysterious planet up to 10 times bigger than Earth, with a distant orbit around the Sun, has been unveiled by professor of astrophysics at Imperial College of London, Michael Rowan-Robinson. Aiming to prove – or rule out – the existence of another big planet beyond Neptune, the UK scientist decided to conduct a new analysis of data collected by the Infrared Astronomical Satellite (IRAS) in 1983.
The astronomer has looked through some 250,000 point sources detected by the telescope, which took a far-infrared survey of 96% of the sky. Having analyzed the data, keeping in mind the hypothetical planet’s size and distance, “at the very limit of the survey,” he singled out a moving object that the satellite picked out on three occasions.
The candidate for Planet 9 would be up to five times the mass of Earth, according to the IRAS data. Its orbital distance would be some 225 times farther than that of our planet, equaling about 33.7 billion kilometers (20.9 billion miles) from the Sun.
If the enigmatic object is indeed rotating around the Sun at such a distance, it would be extremely cold and not much sunlight would be reflected by it, making it even more elusive and harder to find. While the latest study is not a clear detection, it could be valuable as guidance for where exactly to search for the new planet, the astronomer concluded.
“Given the great interest of the Planet 9 hypothesis, it would be worthwhile to check whether an object with the proposed parameters and in the region of sky proposed, is inconsistent with the planetary ephemerides,” he wrote in the preprint paper, accepted for publication in the Monthly Notices of the Royal Astronomical Society.
A debate on the possible existence of an undiscovered planet in our solar system has been ongoing for decades. With no concrete evidence found, there has been speculation about its presence, mainly based on the gravitational clustering of objects in the system’s outer reaches. Several years ago, a suggestion was put forward that a group of icy objects that lie beyond the orbit of Neptune in the Kuiper Belt are possibly under the gravitational influence of a larger mysterious body, possibly Planet 9. The claim was based not on observation, but on modeling.
Currently, the eighth and farthest known planet from the Sun is Neptune. In the last century, Pluto, discovered in 1930, was regarded as the ninth planet, but a controversial vote at the International Astronomical Union (IAU) in 2006 formally excluded it from the solar system’s ‘planets’, and reclassified it as a dwarf planet.
Palestinian Islamist group Hamas has called on Canadian singer Justin Bieber to cancel his upcoming concert in what it calls the “Zionist occupation state” of Israel.
Bieber announced his 2022 world tour dates this week, with a concert in Tel Aviv planned for next October. On Thursday, Hamas’ Artistic Production Department issued a statement, cited by the Palestinian Sawa news outlet, “condemning and denouncing” the performer. It called on the star to cancel the show and “boycott the Zionist occupation state in protest at its repeated crimes against the Palestinian people.”
Bieber has performed in Israel multiple times, his last performance there having been in 2017 at Park HaYarkon – the same venue slated for next year. Since the announcement of the ‘Justice’ tour dates, calls for him to cancel the Tel Aviv show have gained momentum across social media, with many posters condemning the singer for supporting what one called an “apartheid state.”
Some noted that Bieber was set to arrive in Israel after performing in South Africa. “Justin Bieber is really going straight from SA to Israel. From a country that fought apartheid to a country that’s practicing apartheid,” one Twitter user complained.
A petition asking the singer to boycott Israel and exclude it from his tour has been launched online, and had garnered some 3,700 signatures by Friday.
In 2018, the New Zealand singer Lorde canceled a concert in Israel, subsequently thanking fans for “educating” her on the issue, and, the same year, US artist Lana Del Rey at first defended her decision to perform in the country, saying her appearance would not be a “political statement,” before backtracking and canceling the gig.
Hamas has been designated a terrorist group by the US, the EU, and, as of Friday, the UK. In April 2021, international non-governmental organization Human Rights Watch concluded in a report that Israel had committed “crimes against humanity of apartheid and persecution.”
