Scientists have used artificial intelligence to “predict” formulas for new designer drugs, with the stated goal of helping to improve their regulation. The AI generated formulas for nearly nine million potential new drugs.

Researchers with the University of British Columbia (UBC) used a deep neural net for the job, teaching it to make up chemical structures of potential new drugs. According to their study, released this week, the computer intelligence fared better at the task than the scientists had expected.

The research team used a database of known designer drugs – synthetic psychoactive substances – to train the AI on their structures. The market for designer drugs is ever-changing, since their manufacturers are constantly tweaking their formulas to circumvent restrictions and produce new “legal” substances, while cracking their structure takes months for law enforcement agencies, the researchers said.

Read more

FILE PHOTO: A man living on the streets displays what he says is the synthetic drug fentanyl, in the Tenderloin section of San Francisco, California, February 27, 2020 © Reuters / Shannon Stapleton
Drug overdose deaths in US hit all-time record

“The vast majority of these designer drugs have never been tested in humans and are completely unregulated. They are a major public-health concern to emergency departments across the world,” one of the researchers, UBC medical student Dr. Michael Skinnider has said.

After its training, the AI was able to generate some 8.9 million potential designer drugs. Afterwards, researchers ran a data sheet of some 196 new drugs, which had emerged in real life after the model was trained, and found that more than 90% of these have been already predicted by the computer.

“The fact that we can predict what designer drugs are likely to emerge on the market before they actually appear is a bit like the 2002 sci-fi movie, Minority Report, where foreknowledge about criminal activities about to take place helped significantly reduce crime in a future world,” senior author Dr. David Wishart, a professor of computing science at the University of Alberta, has said.

Identifying completely unknown substances remains an issue for the AI, the research team has noted, but they hope it might potentially help with that task, since the computer was also able to predict which formulas of designer drugs were more likely to be created and hit the market. The model “ranked the correct chemical structure of an unidentified designer drug among the top 10 candidates 72 percent of the time,” while throwing in spectrometry analysis, which is an easily obtained measurement, bumped the accuracy to some 86%.

“It was shocking to us that the model performed this well, because elucidating entire chemical structures from just an accurate mass measurement is generally thought to be an unsolvable problem,” Skinnider stated.

Think your friends would be interested? Share this story!

find more fun & mates at SoShow now !

France shouldn’t remain silent on Julian Assange, leftist leader Jean-Luc Melenchon has said, after the imprisoned WikiLeaks co-founder’s father suggested that Paris could offer asylum to his son.

The life of Assange – who is being held in solitary confinement at London’s Belmarsh maximum security prison while a British court considers an extradition request by the US – is under threat, Melenchon wrote on Twitter on Tuesday.

“For years, we’ve been calling for France to accept him,” the head of the leftist La France Insoumise (France Unbowed) party said, insisting that “France shouldn’t remain silent.”

The statement by Melenchon, who won 19.6% of the ballot in the first round of the French presidential election in 2017, follows a visit by Assange’s father, John Shipton, to the Whistleblower Meeting in Paris on Monday.

During the event, Shipton told Sputnik news agency that it would be “an honorable thing” for the French government to grant his son asylum. 

“I feel that France hasn’t attacked Julian over the last 12 years and consequently France is free to act in return for the information that WikiLeaks and Julian brought to France,” he said, referring to the website’s revelations of the US intelligence agencies spying on French presidents and hacking into local banks.

Several dozen French lawmakers have also recently called upon Paris to take Assange in, with the Australian-born publisher’s legal team saying last year that their client was hoping to find asylum on French soil.

Read more

FILE PHOTO: Julian Assange and partner Stella Moris are seen in an undated photo shared by Moris on social media November 11, 2021.
UK caves, allows Assange to get married in jail

Assange could face up to 175 years behind bars if he’s extradited to the US, where he’s wanted on espionage charges over the release by WikiLeaks of classified documents on Iraq, Afghanistan, Guantanamo Bay, and others.

He was placed in Belmarsh in April 2019 over breach of bail, after being holed up in the Ecuadorian Embassy in London for seven years.

The publisher had been fleeing an arrest warrant issued over sexual assault allegations which he has always denied, and which failed to result in any actual charges due to lack of evidence.

Assange’s supporters insist that he has actually been persecuted over his legitimate journalistic activities and revealing the truth to the public.

The UK High Court is expected to rule on the appeal by the US against a lower court decision to bar the WikiLeaks co-founder’s extradition to America due to the 50-year-old’s poor health condition and risk of suicide.

Assange’s team will then be able to challenge the ruling in the Supreme Court if it’s not favorable.

Think your friends would be interested? Share this story!

find more fun & mates at SoShow now !

As India is mulling new rules for digital money, Prime Minister Narendra Modi has called for regulations to ensure cryptocurrencies like bitcoin do not “end up in the wrong hands,” warning that this could “spoil” young people.

While he did not expand on those concerns, Modi spoke on Thursday about the need for “democratic nations” to band together and deal with challenges posed by emerging technologies. He was delivering a virtual address at the Sydney Dialogue, an annual cyber-tech summit.

Noting that technology and data could either become “new weapons” for conflict or “instruments of cooperation,” Modi brought up digital currencies as an example of how it was important that like-minded nations “work together on this” to “ensure it does not end up in the wrong hands, which can spoil our youth.”

We are at a historic moment of choice. Whether all the wonderful powers of technology of our age will be instruments of cooperation or conflict, coercion or choice, domination or development, oppression or opportunity.

He also urged the development of technical and governance standards and norms, singling out the use of data, and called for renewed efforts to prevent manipulation of public opinion. In recent weeks, Indian authorities have raised concerns over claims of huge returns from cryptocurrency investment as well as its potential connections to money laundering, organized crime and terror financing.

Read more

© AP Photo / Charles Krupa
Bitcoin crashes after China rules all crypto-related transactions illegal

On Saturday, Modi chaired a meeting to formulate the country’s approach to digital currencies and examine their impact on the economy. According to The Economic Times, Indian officials are drafting regulations to propose a ban on all transactions and payments in cryptocurrencies, while allowing investors to hold them as assets, similar to gold, bonds and stock shares.

Citing unnamed sources familiar with the government’s discussions, the newspaper said there was a belief in policy circles that crypto markets needed to be regulated in order to tackle the problem of opaque advertising that exaggerates investment returns in order to attract young investors.

The sources informed the newspaper that draft legislation on the matter was expected to be forwarded to Modi’s cabinet for consideration in the next two to three weeks.

In September, China had banned all cryptocurrency transactions and crypto-mining.

If you like this story, share it with a friend!

find more fun & mates at SoShow now !

Rotterdam Mayor Ahmed Aboutaleb has described an anti-lockdown protest in his city as an “orgy of violence.” The Dutch demonstration devolved into a violent riot that saw police open fire on protesters.

Aboutaleb described the events of Friday night as an “orgy of violence,” after protesters packed Rotterdam’s central Coolsingel shopping street to voice their opposition to an ongoing partial lockdown, a ban on New Year’s Eve fireworks displays, and the possibility of a two-tiered system of freedom in the Netherlands, one of liberty for the vaccinated and restrictions for those without the jab.

Read more

A police squad car is seen engulfed in flames during a protest in Rotterdam, Netherlands, November 19, 2021.
2 wounded after shots fired at Covid protest in Netherlands

The protest soon got out of hand, and police said on Saturday that 57 people were arrested. Protesters were seen torching police vehicles and launching fireworks at police, who shot at them in response.

Aboutaleb said that the cops had been “forced” to use their weapons. “On a number of occasions the police felt it necessary to draw their weapons to defend themselves,” he told reporters. “They shot at protesters, people were injured.”

Police say at least seven people were injured. Two of these injuries were caused by police bullets, and the victims are still in hospital. One officer was hospitalized, while several others were treated at the scene for minor injuries.

Like this story? Share it with a friend!

find more fun & mates at SoShow now !

Brazil’s former President Luiz Inacio Lula da Silva has said he is willing to stand as a candidate in elections against incumbent leader Jair Bolsonaro, labelling his potential opponent “a poor copy of Trump.”

Speaking in Brussels at a media conference in the European Parliament on Monday, Lula announced that the Workers Party needs to put forward a presidential candidate to take over from right-wing Bolsonaro in 2022 and said he was willing to run in the elections again.  

Read more

Grounded China Southern Airlines Boeing 737 MAX aircraft at Urumqi airport, in China's western Xinjiiang region, June 5, 2019.
World’s biggest aviation market may soon welcome back exiled Boeing 737 MAX

“I’m willing, I’m motivated, I’m in good health,” Lula stated, adding that said he would only make his decision early next year, some months before the election scheduled for October 2022. The popular leftist said his candidacy would depend on whether the party wanted him. 

“We need to have someone who stands, we need to win the elections. And at the same time, we have to rebuild Brazil,” he said, speaking on behalf of his Workers Party.

Lula, 76, also took aim at the incumbent president. “He’s a poor copy of Trump. But Bolsonaro doesn’t think, he doesn’t have any ideas,” the former president said, claiming the incumbent leader was hellbent on ensuring the beneficial legacies of Lula’s administration were “torn down.” 

A recent poll put him 27 points ahead of Bolsonaro, despite his candidacy not officially being announced.  

In 2010, Lula made way for his protégé, Dilma Rousseff. Rousseff was ousted from power in what was described by her supporters as a parliamentary coup. Lula served nearly two years in prison after being convicted on money laundering and corruption, despite a nine-and-a-half-year sentence. He was also barred from running in the 2018 election. 

A number of judges have subsequently ruled that the case against Lula was unlawful and the Supreme Court annulled his earlier convictions, meaning he can face off against Bolsonaro in 2022.

If you like this story, share it with a friend!

find more fun & mates at SoShow now !

An object lurking in the outer region of our solar system may well be the elusive Planet 9, a leading British astronomer has suggested after digging through the telescope archives of 250,000 point sources.

Possible evidence of a mysterious planet up to 10 times bigger than Earth, with a distant orbit around the Sun, has been unveiled by professor of astrophysics at Imperial College of London, Michael Rowan-Robinson. Aiming to prove – or rule out – the existence of another big planet beyond Neptune, the UK scientist decided to conduct a new analysis of data collected by the Infrared Astronomical Satellite (IRAS) in 1983.

Read more

Courtesy NASA TV
NASA’s Lucy mission blasted into outer solar system to study Trojan asteroids & planetary evolution (VIDEO)

The astronomer has looked through some 250,000 point sources detected by the telescope, which took a far-infrared survey of 96% of the sky. Having analyzed the data, keeping in mind the hypothetical planet’s size and distance, “at the very limit of the survey,” he singled out a moving object that the satellite picked out on three occasions.

The candidate for Planet 9 would be up to five times the mass of Earth, according to the IRAS data. Its orbital distance would be some 225 times farther than that of our planet, equaling about 33.7 billion kilometers (20.9 billion miles) from the Sun. 

READ MORE: Astronomers find exoplanet with unusual orbit

If the enigmatic object is indeed rotating around the Sun at such a distance, it would be extremely cold and not much sunlight would be reflected by it, making it even more elusive and harder to find. While the latest study is not a clear detection, it could be valuable as guidance for where exactly to search for the new planet, the astronomer concluded. 

Given the great interest of the Planet 9 hypothesis, it would be worthwhile to check whether an object with the proposed parameters and in the region of sky proposed, is inconsistent with the planetary ephemerides,” he wrote in the preprint paper, accepted for publication in the Monthly Notices of the Royal Astronomical Society. 

A debate on the possible existence of an undiscovered planet in our solar system has been ongoing for decades. With no concrete evidence found, there has been speculation about its presence, mainly based on the gravitational clustering of objects in the system’s outer reaches. Several years ago, a suggestion was put forward that a group of icy objects that lie beyond the orbit of Neptune in the Kuiper Belt are possibly under the gravitational influence of a larger mysterious body, possibly Planet 9. The claim was based not on observation, but on modeling. 

Currently, the eighth and farthest known planet from the Sun is Neptune. In the last century, Pluto, discovered in 1930, was regarded as the ninth planet, but a controversial vote at the International Astronomical Union (IAU) in 2006 formally excluded it from the solar system’s ‘planets’, and reclassified it as a dwarf planet.

Like this story? Share it with a friend!

find more fun & mates at SoShow now !

Sporadic clashes broke out at massive Saturday demonstrations in major European cities, as thousands of people took to the streets of Vienna, Paris and Rome to express their discontent with Covid-19 restrictions.

The Austrian capital Vienna on Saturday saw the largest protest turnout since the start of the Covid-19 pandemic. A total of 38,000 people took to the city streets to join a dozen demonstrations protesting government measures.

The protests came a day after the Austrian authorities ordered nationwide compulsory vaccination from February 1 and imposed a full lockdown, starting Monday. The massive procession that spanned over several kilometers marched along Vienna’s central ring road. The city center was paralyzed for several hours as traffic was restricted.

Austria’s right-wing Freedom Party, whose members joined the rallies, put the number of protesters at 100,000. Some demonstrations were also attended by members of various far-right groups. The protests were generally peaceful but footage published by Ruptly video news agency showed several scuffles between the police and the demonstrators breaking out.

Law enforcement spoke of a total of five arrests. One incident saw a protester attempting to grab an officer’s gun and take it from its holster. In another incident, the officers were pelted with bottles and fireworks and had to use pepper spray in response.

Hundreds of kilometers away from Vienna, in the French capital Paris, events took a more dramatic turn. There, a demonstration against the government Covid-19 measures coincided with the third anniversary of the Yellow Vests movement. Hundreds of protesters took part in the protest, which quickly turned into clashes between the demonstrators and law enforcement.

The protesters were building barricades and setting them on fire as well as pelting police with bottles and various other projectiles. Law enforcement responded with profuse amounts of tear gas, sometimes filling entire streets with thick smoke to disperse the crowds.

Rome saw a massive demonstration against Italy’s Covid-19 health pass, also known as the Green Pass. Some 4,000 people gathered in the center of the Italian capital, according to the police. The demonstrators were waving national flags and chanting “Freedom” and “No Green Pass,” referring to the vaccination certificate needed to enter various public venues such as clubs or bars.

The crowd staged a sit-in in the Circus Maximus – an ancient Roman chariot-racing stadium converted into a modern-day park. They remained there after sunset, lighting the area with thousands of phones and colored smoke bombs. The rally was peaceful, though, as the police did not report any incidents.

Unlike Rome, Italy’s northern city of Milano saw clashes between protesters and the police as law enforcement officers sought to break up an unauthorized rally at the city center. Large police forces were deployed to the city center and several squares were cordoned off.

Think your friends would be interested? Share this story!

find more fun & mates at SoShow now !