Japan’s fifth wave of Covid-19 has virtually disappeared so dramatically that some scientists are puzzled as to why it happened. One team suggests the highly infectious Delta strain mutated into extinction on the island nation.
In mid-August, Japan experienced a peak in Covid-19 infections, recording over 23,000 new cases per day. Now the metric is just around 170, with deaths attributed to the disease mostly remaining in single digits this month.
The decline has been attributed by many to high vaccination rates, public acceptance of masks, and other factors, but some researchers say the drop was uniquely significant, compared to other nations with similar conditions.
Ituro Inoue, a geneticist at the National Institute of Genetics, believes that Japan had the good fortune of witnessing the Delta strain mostly rooting out other variants of the SARS-CoV-2 virus before then eradicating itself. He explained his team’s theory to the Japan Times newspaper this week.
For some time now, Inoue and his fellow scientists were researching mutations of SARS-CoV-2 and how they are affected by the protein nsp14, which is crucial for the reproduction of the virus.
RNA viruses, like the one causing Covid-19, tend to have a very high mutation rate, which helps them quickly adapt to changes in the environment. However, this opens the door for a so-called “error catastrophe,” when bad mutations pile up and finally cause the full extinction of a strain. The protein nsp14 appears to offer a form of error proofreading that helps the virus genome to stay below the threshold of the “error catastrophe.”
In the case of Japan’s fifth wave of Covid-19, the Delta variant’s nsp14 failed at this job, Inoue believes, based on the genetic study of specimens collected from June to October. Contrary to his team’s expectations, there was a lack of genetic diversity, while many samples had many genetic changes in the site called A394V, which is linked to the error-fixing protein.
“We were literally shocked to see the findings,” the researcher told the Japan Times. “The Delta variant in Japan was highly transmissible and [was] keeping other variants out. But as the mutations piled up, we believe it eventually became a faulty virus and it was unable to make copies of itself.”
The theory could be relevant to the previous SARS strain, which was identified in 2003, explaining why it didn’t cause a pandemic. But that would be hard to confirm, since the outbreak ended relatively quickly and didn’t result in the massive collection of genetic data necessary to test the hypothesis.
It’s not clear why Japan had this lucky turn of events, but nothing comparable happened in other East Asian countries like South Korea, where populations are genetically close to that of Japan. Virus mutations similar to those flagged by the scientists have been discovered in at least 24 countries, Inoue said. He and his team plan to publish a paper detailing their findings by the end of November.
Even if the natural extinction theory is confirmed, it is at best a temporary reprieve for the Japanese people. New, more successful strains are likely to eventually find their way into the country, though quarantine measures and immigration control could delay the emergence of new variants in Japan, Inoue believes.
Meanwhile, Tokyo is bracing for a new wave of Covid-19 this winter and is preparing to live with the virus. The government reportedly plans to ease travel restrictions by increasing the number of people it allows to enter the country per day from 3,500 to 5,000.
The city council in Austria’s second-largest city, Graz, has elected a new mayor. Communist Party member Elke Kahr has become the first Communist leader of a major city in the country.
The 60-year-old politician, who has been working in the municipal government for more than 15 years and previously served as vice mayor of Graz, was elected as the new city leader on Wednesday. A member of the Austrian Communist Party (KPÖ, Kommunistische Partei Österreichs) for almost 30 years, she won the election with 28 of 46 votes. Kahr succeeded the previous long-standing mayor Siegfried Nagl of the center-right, liberal-conservative People’s Party.
“Who would have thought that the daughter of a locksmith, a Communist, would become mayor,” she said in her first speech following the vote.
Having acknowledged a number of issues to deal with in the city, especially during the Covid-19 pandemic, the new mayor highlighted a housing policy, pledging to put a stop to profit-driven construction in Ganz.
The Communists have also already formed a coalition with the Greens and the Social Democratic Party (SPÖ), and another precedent in European city governance was made – two women serving as mayor and deputy. Green leader Judith Schwentner was chosen as Graz’s vice mayor, with the new governing coalition saying they would support not only social, but also environmental changes, aiming to improve living standards especially for low-income groups. Providing a bicycle for every child in the city from the municipality is in their program.
However, not everyone in the local government is happy with the new Communist rule. A member of the right-wing Freedom Party of Austria (FPÖ), Alexis Pascuttini, described the choice as “unpleasant,” having accused the Graz Communists of empty catchphrases in their program and refusing to participate in what he described as “left-wing nonsense.” Kahr herself has been exposed to strong pressure to justify her party, being repeatedly asked about her position on “the crimes of communist parties around the world since 1917,” according to Austrian media.
The annual migration of red crabs has brought traffic to a standstill on an Australian island. Apart from the epic journey, the species is also notorious for eating its own young.
Tens of millions of crustaceans are swarming Canberra-governed Christmas Island, which is almost a thousand miles northwest of the Australian mainland. Parks Australia, a government body in charge of wildlife conservation on the island, has deployed its staff to manage traffic, rake crabs off roads and provide advisories to local residents regarding road closures. Authorities are well-prepared to deal with the epic crab march as it repeats every year, usually in October and November. There are even special bridges and tunnels in place, built over and under busy roads so as to minimize the number of crabs crushed by cars. The sight of millions of these creatures making their perilous trek has become one of Christmas Island’s main tourist attractions.
The exact timing of the red crabs’ journey from forest to ocean is defined by rainfall and lunar phases. The march is led by male crabs, which are later joined by females. On reaching the ocean, they mate and spawn, with each female capable of producing as many as 100,000 eggs. However, most of the young crabs never make it back to the forest as they end up being eaten by fish and whale sharks for whom this is a veritable feast. To make matters worse, the crab larvae that do make it to the beach are often devoured by returning adult crabs of the very same species, hence one of their names – the cannibal crab.
People around the world will need to get a jab against Covid-19 once a year, at least when it comes to the Pfizer vaccine, BioNTech’s CEO Ugur Sahin said in an interview on Sunday, as he praised the quality of its booster shot.
In an interview with Germany’s Bild newspaper on Sunday, Sahin said he considers the vaccine, co-developed by his company, to be “very effective.”
When asked whether people should be worried about the “breakthrough infections” – in which those vaccinated with the Pfizer-BioNTech vaccine still developed Covid-19 symptoms – he dismissed such concerns, saying that the jab offers a “90 percent protection” against cases that require intensive care in those aged over 60.
A “very high” level of protection against severe illness lasts for up to nine months, the BioNTech CEO maintained. He said this level starts decreasing “from the fourth month,” however. To maintain the protection, Sahin strongly pushed for booster shots, arguing that they would not just restore levels of antibodies but would potentially help “to break … chains of infection.”
He also encouraged doctors to be “as pragmatic as possible” when it comes to greenlighting vaccination and “not to send people home unvaccinated even though they could be vaccinated without any problems.”
In the future, people might need to get booster shots once a year, the BioNTech CEO believes. He said that he expects protection from a booster shot to “last longer” than the initial immunity one acquires after getting two doses of the vaccine.
“Subsequent … vaccinations may only be needed every year – just like [with] influenza,” he said. Currently, the German Federal Center for Health Education – an agency subordinated to the Health Ministry – recommends a booster shot six months after one gets the second dose of a vaccine. It also says that “booster vaccination makes sense after a minimum interval of about four months.”
Sahin’s interview comes days after it was revealed that Pfizer, BioNTech and Moderna are making a combined profit of $65,000 every minute – all thanks to their Covid-19 jabs. That is according to estimates made by the People’s Vaccine Alliance (PVA) – a coalition demanding wider access to vaccines.
The PVA estimated that the three companies are to earn a total of $34 billion in combined pre-tax profits this year alone, which roughly translates into more than $1,000 a second and $93.5 million a day.
PVA has slammed the three companies over their refusal to allow vaccine technology transfer despite receiving a combined $8 billion in public funding. Such a move could increase global supply and save millions of lives as well as drive down prices, the coalition said.
“Pfizer, BioNTech and Moderna have used their monopolies to prioritize the most profitable contracts with the richest governments, leaving low-income countries out in the cold,” said Maaza Seyoum of the African Alliance and People’s Vaccine Alliance Africa.
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American billionaire Bill Gates has claimed Covid-19 deaths and infections may drop below seasonal flu levels next year as more people get vaccinated and treatment improves, unless we encounter a new, more deadly variant.
Speaking on Thursday in a virtual interview at the Bloomberg New Economy Forum in Singapore, founder of Microsoft stated that vaccines, natural immunity and emerging oral treatments mean that “the death rate and the disease rate ought to be coming down pretty dramatically.”
The tech mogul, who has been particularly vocal during the pandemic, said issues around vaccine-production capacity are likely to be replaced by distribution challenges and even waning demand.
“The vaccines are very good news, and the supply constraints will be largely solved as we get out in the middle of next year, and so we’ll be limited by the logistics and the demand,” he noted.
He also told his audience that it remains to be seen how much demand there is for Covid-19 shots in places like Sub-Saharan Africa.
Calling for more work to eradicate flu, Gates claimed Covid-19 rates and deaths would possibly fall below those of flu by the middle of next year, unless more deadly coronavirus variants emerge.
The Bill and Melinda Gates Foundation has involved itself in the development of vaccines and virus surveillance, calling for a global response to the Covid-19 pandemic. The foundation has invested hundreds of millions dollars in the development and distribution of potentially lifesaving shots.
According to the World Health Organization, influenza kills up to 650,000 people each year. At least five million people have died from Covid-19 since the pandemic began in late 2019.
When the PRC decides to move on Taiwan, it is unlikely to move in a manner that makes a US decision on intervention clear cut. Should China decide, initially at least, against a full-scale invasion of that island nation, it could instead opt to try to “win without fighting.” Beijing might do so by using its large, state-controlled fishing fleet to cut smaller Taipei-controlled islands off from Taiwan itself much as the PRC is now massing fishing boats to expand Chinese-controlled seas to press claims on the Japanese Senkakus and Whitsun Reef in Philippine waters. Chinese state-owned fisheries companies – part of the so-called ‘Maritime Militia’ – serve as fronts for PLA intelligence. Using their fleets to operate in a manner somewhere between peace and conflict in the gray zone of contested control around Taiwan would allow Beijing to test whether the US and its allies are willing to help defend the island’s independence without being seen to initiate open conflict.
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French luxury giant Dior has taken down a controversial photograph that had been criticized in China for “smearing Asian women” by pandering to Western stereotypes while “distorting Chinese culture.”
The photo, which was part of the brand’s ‘Lady Dior’ exhibition in Shanghai, depicts an Asian model wearing a traditional dress and clutching a Dior handbag. It came under fire this week from Chinese media outlets for featuring “spooky eyes, [a] gloomy face and Qing Dynasty-styled nail armor.”
Although Dior has not released a statement regarding the controversy, it confirmed to fashion trade publication Business of Fashion that the photo had been removed from the exhibition. The brand has also reportedly taken the photo off Chinese social media platform Weibo.
The image, which was shot by Chinese photographer Chen Man, had drawn both media ire and public outrage. However, there were apparently no calls for a boycott of the brand.
In an editorial on Monday titled “Is This the Asian Woman in Dior’s Eyes?”, the Beijing Daily paper had noted that the image makes Chinese consumers uncomfortable. The publication criticized Man for “playing up to the brands, or the aesthetic tastes of the Western world.”
For years, Asian women have always appeared with small eyes and freckles from the Western perspective, but the Chinese way to appreciate art and beauty can’t be distorted by that.
Warning that both the brand and the photographer had “gone too far,” the China Women’s News paper ran an editorial on Wednesday that claimed it “indicated their intention of uglifying Chinese women and distorting Chinese culture.”
“Again, from… Dior’s ghost-style picture, which makes the public feel uncomfortable, it’s easy to see some Western brands’ ‘pride and prejudice’ in their aesthetics and culture,” said the newspaper, which is run by the All-China Women’s Federation.
Meanwhile, the Global Times noted that the “lingering controversy could pose a delicate situation” for Dior and other global brands – for whom China’s “massive” luxury market was one of the biggest sources of revenue. The paper said that the Chinese public had become “increasingly sensitive” toward the depiction and treatment of Chinese people and culture by foreign companies.
While pointing out that Chinese social media users had demanded the company and photographer explain their intention, a number of media outlets also highlighted how some netizens had praised the photo as a departure from typical standards of beauty in the country, often characterized by “fair skin and large eyes.”
Hard-line cleric Ebrahim Raisi won Iran’s presidential election on Saturday in a move that is expected to bolster the conservative legacy of the country’s supreme leader, Ayatollah Ali Khamenei.
The decision is not expected to derail ongoing negotiations aimed at restoring the Joint Comprehensive Plan of Action (JCPOA) nuclear deal, even though Mr. Raisi himself is under US sanctions over accusations of human rights abuses. Many voters stayed away from the polls as the outcome had been predicted for months with many progressive candidates barred from running.
“The Islamic Republic has entered a post-revolutionary dynamic in which a fading revolutionary generation seeks to ensure that the rising political leadership sustains their revolutionary ideals,” says Norman T. Roule, former National Intelligence Manager for Iran at ODNI and Cipher Brief Expert. “The regime’s decision to bar so many candidates and the low turnout make this election a historic embarrassment for the regime and its supporters.”
The Cipher Brief talked with Roule about what the election means and what it doesn’t mean when it comes to relations with the west, the progressive movement within Iran and the election’s impact on the oil markets.
“The Cipher Brief has become the most popular outlet for former intelligence officers; no media outlet is even a close second to The Cipher Brief in terms of the number of articles published by formers.” – Sept. 2018, Studies in Intelligence, Vol. 62 No.
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Instagram is looking to channel the anger of its users by introducing a new feature that allows them to report various problems with the app by shaking their phones.
“Have you ever used Instagram and it wasn’t working like it was supposed to? It was just really getting you… really just pissing you off?” Instagram’s head Adam Mosseri asked his followers in a clip uploaded to Twitter on Wednesday.
Well, precisely for infuriating situations like that, the platform has developed a feature it’s calling “rage shake,” he announced.
Shaking your phone will, from now on, cause a special form to pop up on screen, allowing you to instantly report issues such as photos not uploading or audio not playing.
The form is also the perfect place to let out “all the emotions and feels you’ve got going on,” Mosseri insisted, assuring Instagrammers that these reports would be promptly dealt with.
Thanks to their feedback, Instagram will be able to optimize its bug-fixing process, he said. The option, which he described as a “hidden gem,” is so far available only in the US, on both iOS and Android.
The Instagram boss gently shook his own cellphone in the clip to demonstrate the feature in action. However, it’s likely upset users may well end up rage-shaking with a good deal more passion, which could increase the risk of a gadget being damaged, or their owner or even a passerby being struck should the phone fly out of their hand.
Mosseri also didn’t advise the public what to do with their rage over media revelations about alleged shady practices by Instagram and the platform’s owner, Facebook.
Among the trove of papers recently leaked by former Facebook employee Frances Haugen was an internal study from 2020 reporting that Instagram was causing many of its young users, particularly teen girls, to suffer mental health issues and suicidal thoughts. However, the platform kept operating in the same manner despite this finding, with changes being promised only after the study made headlines this September.
Taiwan’s president unveiled the country’s combat wing of advanced US-made F-16 fighters in a ceremony on Thursday, showing its new Air Force capabilities against mainland China.
The event, held at an air base in the southern Taiwanese city of Chiayi, saw the island commission the first combat wing of F-16 fighters, developed with US support.
The F-16 upgrades, costing T$110 billion (USD$3.95 billion), have been jointly completed by American manufacturer Lockheed Martin Corp and Taiwan’s Aerospace Industrial Development Corp.
Taiwan’s leader, Tsai Ing-wen, touted the new F-16s as ensuring that the island’s defenses would be “even stronger” in the face of increased tensions with China.
In October, Beijing sent a record 150 warplanes into Taiwan’s air defense identification zone (ADIZ) in four straight days of incursions. Over the past year, China’s Air Force has increased military activity in and around Taiwan’s ADIZ, according to Taipei.
Despite Taipei claiming it does not want to provoke a confrontation with China, the island’s president pledged that it will “do whatever it takes to defend itself.”
China has rejected claims that it is provoking conflict in Taiwan, which it sees as an integral part of its country, accusing America of “inflating” the island separatist movement, firmly stating that “Taiwan independence” is a dead end and Beijing will “take all steps” to ensure the island remains under its control. In recent years, China has become increasingly assertive about reuniting its wealthy island neighbor with the mainland.
The successful F-16 development process has been seen by Taiwan as the latest visible sign of the military partnership between Washington, DC and Taipei. Back in 2019, America approved an $8 billion sale of F-16s to Taiwan, which would bring the total number of jets in the island’s fleet to 200.
During the event, the Taiwanese president praised America for remaining steadfast in its cooperation with the island despite opposition from China. “As long as we adhere to the values of democracy and freedom, there will be more like-minded countries standing on the same front with us,” Tsai said alongside US diplomat Sandra Oudkirk.
In 2019, after the US and Taiwan agreed to upgrade the F-16 fighter jets, then-Foreign Ministry spokesperson Geng Shuang threatened to sanction American firms unless the deal was halted. Beijing opposed the military partnership between Taipei and Washington, DC, arguing that the sale violated international law, harmed relations between the countries, and breached the One China policy, which America recognizes.
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